SCHEMBL272669

SCHEMBL272669

CCCCNCCCC[SiH](OC)OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
ALDH1A1 P00352 1/20 0.50
ADH1B P00325 2/20 0.38
ADH1C P00326 2/20 0.38
ADH1A P07327 2/20 0.38
ADH7 P40394 2/20 0.38
CYP2C19 P33261 2/20 0.37
CYP1A2 P05177 1/20 0.37
S1PR2 O95136 5/20 0.34
S1PR4 O95977 5/20 0.34
S1PR1 P21453 5/20 0.34
S1PR3 Q99500 5/20 0.34
S1PR5 Q9H228 1/20 0.34
KMT2A Q03164 2/20 0.34
SIGMAR1 Q99720 1/20 0.33
MEN1 O00255 1/20 0.33
GLA P06280 1/20 0.33
HRH4 Q9H3N8 2/20 0.33
HRH3 Q9Y5N1 2/20 0.33
EPHX1 P07099 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15360400 0.98 TSHR (0.48) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL15360341 0.93 TSHR (0.46) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL614388 0.91 TSHR (0.44) TSHRALDH1A1ADH1BADH1AADH7
SCHEMBL28975742 0.91 TSHR (0.39) TSHRALDH1A1CYP2C19CYP1A2KMT2A
SCHEMBL15004595 0.89 TSHR (0.54) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL555018 0.89 TSHR (0.46) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL27999229 0.89 TSHR (0.46) TSHRALDH1A1ADH1BADH1CADH1A
Dimethylamine SCHEMBL18630929 0.88 TSHR (0.41) TSHRALDH1A1CYP2C19CYP1A2S1PR2
Hydrochloric Acid SCHEMBL6898636 0.88 TSHR (0.52) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL4326528 0.85 TSHR (0.54) TSHRALDH1A1ADH1BADH1CADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042878-A1 Curable Compositions Comprising At Least One Silane-Modified Polymer HENKEL AG & CO KGAA (DE) 2026-02-12 US claimed
EP-4562072-A1 CROSS-LINKED ORGANOSILICON NETWORKS THAT DEGRADE WITH FLUORIDE SALTS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2025-06-04 EP claimed
EP-4455178-A1 CURABLE COMPOSITIONS COMPRISING AT LEAST ONE SILANE-MODIFIED POLYMER Henkel AG & Co. KGaA (DE) 2024-10-30 EP claimed
US-20240343942-A1 CURABLE SILOXANE-MODIFIED RESIN COMPOSITIONS WITH SILICONE-OIL ADDITIVES AND USE THEREOF THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2024-10-17 US claimed
US-12018122-B2 Method for producing silane-modified polymers MERZ+BENTELI AG (CH) 2024-06-25 US claimed
US-20240043601-A1 CROSS-LINKED ORGANOSILICON NETWORKS THAT DEGRADE WITH FLUORIDE SALTS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2024-02-08 US claimed
WO-2024026227-A1 CROSS-LINKED ORGANOSILICON NETWORKS THAT DEGRADE WITH FLUORIDE SALTS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2024-02-01 WO claimed
EP-3476876-B1 PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS MOMENTIVE PERFORMANCE MAT INC (US) 2023-08-09 EP claimed
EP-3877438-B1 METHOD FOR THE PREPARATION OF SILANE-MODIFIED POLYMERS MERZ BENTELI AG (CH) 2023-06-14 EP claimed
CN-113166358-B Process for preparing silane-modified polymers 默兹奔特利股份公司 2023-03-28 CN claimed
US-20110319555-A1 SINGLE-COMPONENT COATING HAVING ALKOXYSILANE-TERMINATED N-SUBSTITTUED UREA RESINS SCIENCE APPLICATIONS INTERNATIONAL CORPORATION 2011-12-29 US claimed
EP-1678267-B1 COMPOSITION FOR PRODUCING A BARRIER LAYER FOR GASES EVONIK DEGUSSA GMBH (DE) 2011-12-21 EP claimed
EP-1718689-B1 SILANE FORMULATION FOR MOISTURE-CROSSLINKING HYBRID ADHESIVES AND SEALANTS EVONIK DEGUSSA GMBH (DE) 2010-03-10 EP claimed
JP-2007513212-A 2007-05-24 JP claimed
US-20070099004-A1 Composition for producing a barrier layer for gases DEGUSSA AG (DE) 2007-05-03 US claimed
EP-1678267-A1 COMPOSITION FOR PRODUCING A BARRIER LAYER FOR GASES Degussa AG (DE) 2006-07-12 EP claimed
EP-1245601-B1 Metalfree silane terminated polyurethanes, a process for their preparation and their use DEGUSSA (DE) 2006-05-17 EP claimed
WO-2005040294-A1 COMPOSITION FOR PRODUCING A BARRIER LAYER FOR GASES DEGUSSA AG (DE) 2005-05-06 WO claimed
US-6784272-B2 REACTING AMINOALKYLALKOXYSILANE WITH A POLYURETHANE PREPOLYMER THAT HAS TERMINAL ISOCYANATE GROUP IN THE ABSENCE OF A METAL CATALYST DEGUSSA AG (DE) 2004-08-31 US claimed
US-20020188068-A1 Metal-free silane-terminated polyurethanes, a process for their preparation and their use DEGUSSA AG (DE) 2002-12-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042878-A1 Curable Compositions Comprising At Least One Silane-Modified Polymer CDH1, MECP2, COL14A1 TSHR 4253/4885ALDH1A1 2682/4885ADH1B 4448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.