Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4328296 | 1.00 | PARP1 (0.61) | PARP1ERCC5FEN1MEN1KMT2A | |
| SCHEMBL4328293 | 1.00 | PARP1 (0.61) | PARP1ERCC5FEN1MEN1KMT2A | |
| SCHEMBL8937297 | 0.81 | PARP1 (0.55) | PARP1ERCC5FEN1MEN1KMT2A | |
| SCHEMBL11121569 | 0.80 | PARP1 (0.53) | PARP1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL11121567 | 0.80 | PARP1 (0.53) | PARP1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL15384456 | 0.79 | PARP1 (0.62) | PARP1ERCC5FEN1MEN1KMT2A | |
| SCHEMBL6704885 | 0.79 | PARP1 (0.52) | PARP1ERCC5FEN1MEN1KMT2A | |
| SCHEMBL9512846 | 0.79 | PARP1 (0.52) | PARP1ERCC5FEN1MEN1KMT2A | |
| SCHEMBL6704887 | 0.79 | PARP1 (0.52) | PARP1ERCC5FEN1MEN1KMT2A | |
| SCHEMBL4240912 | 0.78 | TDP1 (0.54) | PARP1MEN1KMT2ASMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146696-A1 | USE OF INDOLE-3-CARBOXYLIC ESTERS FOR INHIBITING MICROSOMAL PROSTAGLANDIN E2 SYNTHASE | Universität Tübingen (DE) | 2009-12-10 | — | — | WO | disclosed |