Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430173 | 0.96 | ALDH1A1 (0.32) | ALDH1A1TP53HPGDTDP1CYP2A6 | |
| SCHEMBL430200 | 0.86 | HDAC2 (0.34) | — | |
| SCHEMBL6727408 | 0.85 | ALDH1A1 (0.30) | ALDH1A1TP53HPGDTDP1CYP2A6 | |
| SCHEMBL18873848 | 0.85 | ALDH1A1 (0.30) | ALDH1A1TP53HPGDTDP1CYP2A6 | |
| SCHEMBL431036 | 0.84 | ACACB (0.35) | ALDH1A1HPGD | |
| SCHEMBL12116189 | 0.83 | ALDH1A1 (0.32) | ALDH1A1TP53HPGDTDP1CYP2A6 | |
| SCHEMBL18971697 | 0.83 | ALDH1A1 (0.32) | ALDH1A1TP53HPGDTDP1CYP2A6 | |
| SCHEMBL13065688 | 0.83 | S1PR1 (0.33) | — | |
| SCHEMBL431335 | 0.83 | S1PR1 (0.33) | — | |
| SCHEMBL432546 | 0.82 | EDNRB (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065066-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120065066-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-03-15 | — | — | US | disclosed |
| WO-2010133232-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065066-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | ALDH1A1 14/4885TP53 3477/4885HPGD 2284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.