Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.69 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 8/20 | 0.63 |
| ▸ | RAB9A | P51151 | 8/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.56 |
| ▸ | PLAU | P00749 | 3/20 | 0.56 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.55 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6228356 | 0.83 | DEGS1 (0.74) | DEGS1KMT2AMEN1NR1H4NPC1 | |
| SCHEMBL6932712 | 0.83 | NR1H4 (0.69) | DEGS1KMT2AMEN1NR1H4NPC1 | |
| SCHEMBL26885220 | 0.83 | DEGS1 (0.79) | PTPN1DEGS1KMT2AMEN1NR1H4 | |
| SCHEMBL3066613 | 0.83 | KMT2A (0.66) | PTPN1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2467402 | 0.82 | PLAU (0.78) | PTPN1DEGS1KMT2AMEN1NR1H4 | |
| SCHEMBL220588 | 0.82 | PTPN1 (1.00) | PTPN1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL29411099 | 0.82 | PTPN1 (1.00) | PTPN1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL7890716 | 0.81 | DEGS1 (1.00) | DEGS1KMT2AMEN1NR1H4NPC1 | |
| SCHEMBL3656661 | 0.81 | DEGS1 (0.77) | DEGS1KMT2AMEN1NR1H4NPC1 | |
| SCHEMBL29518660 | 0.81 | DEGS1 (1.00) | DEGS1KMT2AMEN1NR1H4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |