SCHEMBL2467402

SCHEMBL2467402

O=C(Nc1ccccc1)c1ccc2ccccc2c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 2/20 0.78
DEGS1 O15121 1/20 0.78
NPC1 O15118 8/20 0.76
RAB9A P51151 8/20 0.76
KDM4E B2RXH2 1/20 0.76
F2 P00734 1/20 0.73
PLG P00747 1/20 0.73
PLAT P00750 1/20 0.73
KLKB1 P03952 1/20 0.73
KLK1 P06870 1/20 0.73
PRSS1 P07477 1/20 0.73
NR1H4 Q96RI1 1/20 0.72
MEN1 O00255 5/20 0.71
KMT2A Q03164 5/20 0.71
CASP3 P42574 1/20 0.71
SENP7 Q9BQF6 1/20 0.71
GPR27 Q9NS67 1/20 0.71
ENPP3 O14638 1/20 0.65
ENPP1 P22413 1/20 0.65
ENPP2 Q13822 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26885208 0.92 PTPN1 (0.73) PLAUDEGS1NPC1RAB9AKDM4E
SCHEMBL3656661 0.91 DEGS1 (0.77) PLAUDEGS1NPC1RAB9AKDM4E
SCHEMBL14111908 0.91 PLAU (0.76) PLAUDEGS1NPC1RAB9AKDM4E
SCHEMBL15599961 0.90 MEN1 (0.78) PLAUDEGS1NPC1RAB9AKDM4E
SCHEMBL26885220 0.89 DEGS1 (0.79) PLAUDEGS1NPC1RAB9AKDM4E
SCHEMBL26885217 0.89 PTPN1 (0.73) PLAUDEGS1NPC1RAB9AKDM4E
SCHEMBL3031316 0.88 HDAC2 (0.74) PLAUDEGS1NPC1RAB9AKDM4E
SCHEMBL6556069 0.88 DEGS1 (0.77) PLAUDEGS1NPC1RAB9AKDM4E
SCHEMBL29518660 0.88 DEGS1 (1.00) PLAUDEGS1NPC1RAB9AKDM4E
SCHEMBL7890716 0.88 DEGS1 (1.00) PLAUDEGS1NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106310826-A High-efficiency air purification device in garbage disposal system and operating method thereof 徐州工程学院 2017-01-11 CN claimed
CN-103756670-A Organic electroluminescence material as well as preparation method and application thereof SHANGHAI EVERDISPLAY OPTRONICS CO LTD 2014-04-30 CN claimed
CN-1221754-C Flange installation for water drainage, air exhaust and sewage, and its mfg. method XIA XIANGDONG (CN) 2005-10-05 CN claimed
CN-1480676-A Flange installation for water drainage, air exhaust and sewage, and its mfg. method 夏祥东 2004-03-10 CN claimed
WO-2022145110-A1 CORE-SHEATH COMPOSITE FIBER FOR ARTIFICIAL HAIR, HEADWEAR PRODUCT INCLUDING SAME, AND PRODUCTION METHOD FOR SAME 株式会社カネカ 2022-07-07 WO disclosed
CN-109180518-B Secondary/tertiary amide compound and synthesis method thereof 陕西科技大学 2021-05-18 CN disclosed
US-10599060-B2 Toner CANON KABUSHIKI KAISHA (JP) 2020-03-24 US disclosed
CN-106257332-B Electrostatic image developing toner, electrostatic charge image developer, toner Cartridge, handle box, imaging device and imaging method 富士施乐株式会社 2019-11-12 CN disclosed
US-10423090-B2 Magenta toner and toner kit CANON KABUSHIKI KAISHA (JP) 2019-09-24 US disclosed
US-20190171123-A1 MAGENTA TONER AND TONER KIT CANON KABUSHIKI KAISHA (JP) 2019-06-06 US disclosed
US-20190171125-A1 TONER CANON KABUSHIKI KAISHA (JP) 2019-06-06 US disclosed
CN-109180518-A Secondary/teritary amide class the compound of one kind and its synthetic method 陕西科技大学 2019-01-11 CN disclosed
CN-1157288-A Benzimidazole derivatives, their preparation and their therapeutic use SANKYO CO (JP) 1997-08-20 CN disclosed
US-5624935-A ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS OR ANTILIPEMIC AGENTS SANKYO COMPANY, LIMITED 1997-04-29 US disclosed
CN-1118781-A Heterocyclic compound with activity against diabetes and preparation and application of same MITSUTAKA CO LTD (JP) 1996-03-20 CN disclosed
EP-0016581-B1 ZIEGLER TYPE CATALYST COMPOSITION EXXON RESEARCH AND ENGINEERING COMPANY (US) 1984-08-08 EP disclosed
US-4283477-A POLYSULFONAMIDE SEPARATION POLYMER FOR STORAGE STABILITY EASTMAN KODAK COMPANY (US) 1981-08-11 US disclosed
EP-0016581-A1 Ziegler type catalyst composition EXXON RESEARCH AND ENGINEERING COMPANY (US) 1980-10-01 EP disclosed
US-4224182-A POLYMERIZATION CATALYSTS EXXON RESEARCH & ENGINEERING CO. (US) 1980-09-23 US disclosed
US-4153598-A Monoazo and diazo colorants from aminoalkylanilines and bis(aminoalkyl)anilines STERLING DRUG INC. (US) 1979-05-08 US disclosed