SCHEMBL43283

SCHEMBL43283

O=S(=O)(Cl)C1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9773765 1.00
SCHEMBL15971422 1.00
Chloromethane SCHEMBL28145551 0.93
SCHEMBL68569 0.86
SCHEMBL9773703 0.85 EPHX2 (0.33)
SCHEMBL13973741 0.85 LMNA (0.31)
SCHEMBL28539038 0.85
SCHEMBL14641415 0.83 CA1 (0.38)
SCHEMBL14463171 0.83 CA1 (0.38)
SCHEMBL22022206 0.83 CA1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5384 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12320012-B2 Thermal atomic layer etching processes ASM IP HOLDING B.V. (NL) 2025-06-03 US claimed
CN-119708008-A Preparation method of Marbalol Sha Wei intermediate 山东科新药业有限公司 2025-03-28 CN claimed
CN-117886761-A Pyrimidine derivative containing cyclopropane sulfonamido and pharmaceutically acceptable salt thereof, and preparation method and application thereof 广东莱恩医药研究院有限公司 2024-04-16 CN claimed
US-20230374671-A1 THERMAL ATOMIC LAYER ETCHING PROCESSES ASM IP HOLDING B.V. (NL) 2023-11-23 US claimed
CN-115160298-B Tacrine-sulfonamide derivative and preparation method and application thereof 中国人民解放军北部战区总医院 2023-05-23 CN claimed
EP-3601262-B1 PROCESS FOR THE PREPARATION OF A SULFONAMIDE STRUCTURED KINASE INHIBITOR AURIGENE DISCOVERY TECH LTD (IN) 2022-11-09 EP claimed
CN-115160298-A Tacrine-sulfonamide derivative and preparation method and application thereof 中国人民解放军北部战区总医院 2022-10-11 CN claimed
CN-110446704-B Process for the preparation of sulfonamide-structured kinase inhibitors 奥赖恩公司 2022-07-05 CN claimed
CN-113651799-B Six-membered non-aromatic ring-containing diaryl pyrimidine HIV-1 reverse transcriptase inhibitor and preparation method and application thereof 山东大学 2022-06-17 CN claimed
CN-113651799-A Six-membered non-aromatic ring-containing diaryl pyrimidine HIV-1 reverse transcriptase inhibitor and preparation method and application thereof 山东大学 2021-11-16 CN claimed
EP-1833817-B1 SYNTHESIS OF CCR5 RECEPTOR ANTAGONISTS SCHERING CORP (US) 2010-10-13 EP claimed
US-7728135-B2 Synthesis of CCR5 receptor antagonists SCHERING CORPORATION (US) 2010-06-01 US claimed
US-20100063280-A1 PROCESS FOR PREPARING CCR-5 RECEPTOR ANTAGONISTS UTILIZING 4-SUBSTITUTED 1-CYCLOPROPANE-SULFONYL-PIPERIDINYL COMPOUNDS SCHERING CORPORATION 2010-03-11 US claimed
US-20100036125-A1 SYNTHESIS OF CCR5 RECEPTOR ANTAGONISTS SCHERING CORPORATION 2010-02-11 US claimed
EP-2125733-A1 PROCESS FOR PREPARING CCR-5 RECEPTOR ANTAGONISTS UTILIZING 4-SUBSTITUTED 1-CYCLOPROPANE-SULFONYL-PIPERIDINYL COMPOUNDS SCHERING CORPORATION (US) 2009-12-02 EP claimed
WO-2008079284-A1 PROCESS FOR PREPARING CCR-5 RECEPTOR ANTAGONISTS UTILIZING 4-SUBSTITUTED 1-CYCLOPROPANE-SULFONYL-PIPERIDINYL COMPOUNDS SCHERING CORPORATION (US) 2008-07-03 WO claimed
CN-101137646-A Synthesis of CCR5 receptor antagonists SCHERING CORP (US) 2008-03-05 CN claimed
EP-1833817-A2 SYNTHESIS OF CCR5 RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2007-09-19 EP claimed
US-20060258863-A1 Synthesis of CCR5 antagonists SCHERING CORPORATION 2006-11-16 US claimed
WO-2006074270-A2 SYNTHESIS OF CCR5 RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2006-07-13 WO claimed