⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017359 | 0.78 | — | — | |
| SCHEMBL20844169 | 0.74 | — | — | |
| SCHEMBL29825249 | 0.74 | — | — | |
| SCHEMBL14688388 | 0.74 | — | — | |
| SCHEMBL18319850 | 0.74 | — | — | |
| SCHEMBL29963824 | 0.74 | — | — | |
| SCHEMBL16040559 | 0.74 | — | — | |
| SCHEMBL502845 | 0.71 | — | — | |
| SCHEMBL29628989 | 0.71 | — | — | |
| SCHEMBL15284060 | 0.70 | NT5E (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008334-B | A kind of preparation process of the fluoro- 2- ethoxyacetic acid ethyl ester pyridine of the chloro- 6- of 4- amino -3,5- two | 四川福思达生物技术开发有限责任公司 | 2019-02-01 | — | — | CN | claimed |
| CN-103172561-A | Method for synthesizing [(4-amino-3,5-dichloro-6-fluoro-2-pyridinyl)oxy]acetic acid by using one-pot method | YONGNONG BIOSCIENCES CO LTD | 2013-06-26 | — | — | CN | claimed |
| US-20260146047-A1 | MACROCYCLIC HETEROCYCLE COMPOUNDS AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2026-05-28 | — | — | US | disclosed |
| EP-4680611-A1 | MACROCYCLIC HETEROCYCLE COMPOUNDS AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2026-01-21 | — | — | EP | disclosed |
| CN-114945571-B | Cyclic compounds and methods of use thereof | 薛定谔公司 | 2025-02-25 | — | — | CN | disclosed |
| US-20240309016-A1 | MACROCYCLIC HETEROCYCLE COMPOUNDS AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-09-19 | — | — | US | disclosed |
| WO-2024189597-A1 | MACROCYCLIC HETEROCYCLE COMPOUNDS AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-09-19 | — | — | WO | disclosed |
| CN-114269756-B | 4-Oxo-3, 4-dihydropyrido [3,4-D ] pyrimidine compounds that inhibit EIF4E | 效应疗法股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| US-20240101516-A1 | SYNTHESIS OF POLYFLUORINATED ARYL AND HETEROARYL CARBOXAMIDES | BASF SE (DE) | 2024-03-28 | — | — | US | disclosed |
| CN-117229284-B | Tricyclic fused heterocyclic compound, preparation method and application thereof in medicine | 上海泽德曼医药科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| US-20240018157-A1 | CYCLIC COMPOUNDS AND METHODS OF USING SAME | SCHRÖDINGER, INC. | 2024-01-18 | — | — | US | disclosed |
| WO-2007017075-A1 | INSECTICIDAL 3-ACYLAMINOBENZANILIDES | BAYER CROPSCIENCE AG (DE) | 2007-02-15 | — | — | WO | disclosed |
| EP-0556737-B1 | Process for the preparation of substituted 2,3-difluoro-pyridines | CLARIANT GMBH (DE) | 2000-01-12 | — | — | EP | disclosed |
| US-5468863-A | Process for the preparation of substituted 2,3-difluoropyridines | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-11-21 | — | — | US | disclosed |
| EP-0556737-A1 | Process for the preparation of substituted 2,3-difluoro-pyridines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-25 | — | — | EP | disclosed |
| EP-0415498-A2 | Fluorination with hydrogen fluoride | DOWELANCO (US) | 1991-03-06 | — | — | EP | disclosed |
| US-4766219-A | Preparation of 2-cyano-6-chloropyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1988-08-23 | — | — | US | disclosed |
| CN-86108662-A | From Halogenated Pyridine Compounds, remove iron(ic) chloride | — | 1987-09-09 | — | — | CN | disclosed |
| CN-85103731-A | FLUOROPYRIDINYLMETHYL CYCLOPROPANECARBOXYLATE INSECTICIDES AND INTERMEDIATES | — | 1987-01-07 | — | — | CN | disclosed |
| US-3947457-A | Method for preparing 2,5-dihalo- and 2,5,6-trihalopyridines | THE DOW CHEMICAL COMPANY (US) | 1976-03-30 | — | — | US | disclosed |