SCHEMBL8017359

SCHEMBL8017359

Fc1nc(Cl)ccc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18319850 0.79
SCHEMBL432833 0.78
SCHEMBL23025975 0.74
SCHEMBL15994843 0.74
SCHEMBL29825249 0.74
SCHEMBL14688388 0.74
SCHEMBL31361105 0.74
SCHEMBL2371150 0.74
SCHEMBL9982792 0.74
SCHEMBL26944224 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4766219-A Preparation of 2-cyano-6-chloropyridine compounds THE DOW CHEMICAL COMPANY (US) 1988-08-23 US claimed
CN-101671217-A Method for preparing organic chlorofluoro compounds from organic polychlorinated compounds NANJING NO 1 PESTICIDE GROUP C 2010-03-17 CN disclosed
EP-0556737-B1 Process for the preparation of substituted 2,3-difluoro-pyridines CLARIANT GMBH (DE) 2000-01-12 EP disclosed
US-5512207-A Azaaromatic compounds, process for their preparation, and their use in liquid-crystalline mixtures HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-30 US disclosed
US-5468863-A Process for the preparation of substituted 2,3-difluoropyridines HOECHST AKTIENGESELLSCHAFT (DE) 1995-11-21 US disclosed
EP-0556737-A1 Process for the preparation of substituted 2,3-difluoro-pyridines HOECHST AKTIENGESELLSCHAFT (DE) 1993-08-25 EP disclosed
US-4766219-A Preparation of 2-cyano-6-chloropyridine compounds THE DOW CHEMICAL COMPANY (US) 1988-08-23 US disclosed
US-3947457-A Method for preparing 2,5-dihalo- and 2,5,6-trihalopyridines THE DOW CHEMICAL COMPANY (US) 1976-03-30 US disclosed