Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Propionic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.83 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PPARD | Q03181 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL386699 | 1.00 | FFAR3 (0.83) | FFAR3LCKFYNTDP1ALDH1A1 | |
| Propionic Acid SCHEMBL8625749 | 1.00 | FFAR3 (0.83) | FFAR3LCKFYNTDP1ALDH1A1 | |
| Propionic Acid SCHEMBL27684780 | 1.00 | FFAR3 (0.83) | FFAR3LCKFYNTDP1ALDH1A1 | |
| Propionic Acid SCHEMBL27510371 | 1.00 | FFAR3 (0.83) | FFAR3LCKFYNTDP1ALDH1A1 | |
| Propionic Acid SCHEMBL2454431 | 1.00 | FFAR3 (0.83) | FFAR3LCKFYNTDP1ALDH1A1 | |
| Propionic Acid SCHEMBL2461940 | 1.00 | FFAR3 (0.83) | FFAR3LCKFYNTDP1ALDH1A1 | |
| Propionic Acid SCHEMBL608914 | 1.00 | FFAR3 (0.83) | FFAR3LCKFYNTDP1ALDH1A1 | |
| Propionic Acid SCHEMBL35071 | 1.00 | — | — | |
| Propionic Acid SCHEMBL5047359 | 0.96 | FFAR3 (0.77) | FFAR3LCKFYNTDP1ALDH1A1 | |
| Propionic Acid SCHEMBL10882836 | 0.96 | FFAR3 (0.77) | FFAR3LCKFYNTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377640-B1 | AZO COMPOUNDS AND PROCESS OF PRODUCING THE SAME AND NOVEL INTERMEDIATE COMPOUNDS USED IN THE PROCESS OF PRODUCING AZO COMPOUNDS | FUJIFILM CORP (JP) | 2017-05-17 | — | — | EP | disclosed |
| US-7601819-B2 | Azo dye, colored curable composition, color filter and producing method therefor | FUJIFILM CORPORATION (JP) | 2009-10-13 | — | — | US | disclosed |
| US-7572911-B2 | Azo compound and process of producing the same, and novel compound and process of producing azo compounds using the same | FUJIFILM CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| EP-1564259-B1 | Azo dye, colored curable composition, color filter and producing method therefor | FUJIFILM CORP (JP) | 2008-03-12 | — | — | EP | disclosed |
| US-20070173641-A1 | Azo compound and process of producing the same, and novel compound and process of producing azo compounds using the same | FUJI PHOTO FILM CO., LTD. | 2007-07-26 | — | — | US | disclosed |
| US-7109336-B2 | Azo compound and process of producing the same, and novel compound and process of producing azo compounds using the same | FUJI PHOTO FILM CO., LTD. (JP) | 2006-09-19 | — | — | US | disclosed |
| EP-1564259-A1 | Azo dye, colored curable composition, color filter and producing method therefor | FUJI PHOTO FILM CO., LTD. (JP) | 2005-08-17 | — | — | EP | disclosed |
| US-20050175908-A1 | Azo dye, colored curable composition, color filter and producing method therefor | FUJI PHOTO FILM CO., LTD. | 2005-08-11 | — | — | US | disclosed |
| EP-1377640-A2 | AZO COMPOUNDS AND PROCESS OF PRODUCING THE SAME AND NOVEL INTERMEDIATE COMPOUNDS USED IN THE PROCESS OF PRODUCING AZO COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002083662-A2 | AZO COMPOUNDS AND PROCESS OF PRODUCING THE SAME AND NOVEL INTERMEDIATE COMPOUNDS USED IN THE PROCESS OF PRODUCING AZO COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173641-A1 | Azo compound and process of producing the same, and novel compound and process of producing azo compounds using the same | CYP4A11, CYP4F11, CYP4X1 | ESR1 1310/4885FFAR3 4079/4885LCK 3190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.