Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Propionic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.83 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PPARD | Q03181 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL386699 | 1.00 | FFAR3 (0.83) | FFAR3LCKFYNTDP1ALDH1A1 | |
| Propionic Acid SCHEMBL8625749 | 1.00 | FFAR3 (0.83) | FFAR3LCKFYNTDP1ALDH1A1 | |
| Propionic Acid SCHEMBL27684780 | 1.00 | FFAR3 (0.83) | FFAR3LCKFYNTDP1ALDH1A1 | |
| Propionic Acid SCHEMBL27510371 | 1.00 | FFAR3 (0.83) | FFAR3LCKFYNTDP1ALDH1A1 | |
| Propionic Acid SCHEMBL4328390 | 1.00 | FFAR3 (0.83) | FFAR3LCKFYNTDP1ALDH1A1 | |
| Propionic Acid SCHEMBL2461940 | 1.00 | FFAR3 (0.83) | FFAR3LCKFYNTDP1ALDH1A1 | |
| Propionic Acid SCHEMBL608914 | 1.00 | FFAR3 (0.83) | FFAR3LCKFYNTDP1ALDH1A1 | |
| Propionic Acid SCHEMBL35071 | 1.00 | — | — | |
| Propionic Acid SCHEMBL5047359 | 0.96 | FFAR3 (0.77) | FFAR3LCKFYNTDP1ALDH1A1 | |
| Propionic Acid SCHEMBL10882836 | 0.96 | FFAR3 (0.77) | FFAR3LCKFYNTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029918-A1 | Novel antibiotic compounds | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 2004-02-12 | — | — | US | claimed |
| EP-0633896-B1 | ESTERIFIED STARCH COMPOSITION | NAT STARCH CHEM INVEST (US) | 1998-06-17 | — | — | EP | claimed |
| CN-116813804-A | Preparation method of cellulose ester optical material | 四川大学 | 2023-09-29 | — | — | CN | disclosed |
| CN-105555817-B | Use of gel-like polymer compositions obtainable by polymerization of acid group-containing monomers in the presence of polyether compounds in formulations for dishwashing | 巴斯夫欧洲公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-109422956-A | A method of reducing volatile organic content in polypropylene process | 上汽通用五菱汽车股份有限公司 | 2019-03-05 | — | — | CN | disclosed |
| US-9593230-B2 | Plasticized polymeric composition | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-03-14 | — | — | US | disclosed |
| US-20160257802-A1 | PLASTICIZED POLYMERIC COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY | 2016-09-08 | — | — | US | disclosed |
| CN-103319782-B | A kind of PP composite material of low smell and preparation method thereof | 吉林恒辉新材料有限公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-103314094-B | The purposes of the thioether of the optional oxidation of alcohol alkoxylates in washing agent and cleaning agent | BASF SE (DE) | 2016-05-25 | — | — | CN | disclosed |
| CN-105555817-A | Use of gel-like polymer compositions obtainable by polymerization of acid group-containing monomers in the presence of polyether compounds in formulations for dishwashing | BASF SE | 2016-05-04 | — | — | CN | disclosed |
| CN-105518038-A | Solid polymer composition obtained by polymerization of an acid group-containing monomer in the presence of a polyether compound | BASF SE | 2016-04-20 | — | — | CN | disclosed |
| US-20060060997-A1 | Polarizing plate protective film and manufacturing method for the same | KONICA MINOLTA OPTO, INC. | 2006-03-23 | — | — | US | disclosed |
| CN-1506754-A | Concentrated bleaching-fixing agent composition for silver halide colour photographic material | 柯尼卡美能达控股株式会社 | 2004-06-23 | — | — | CN | disclosed |
| US-5587412-A | MELT PROCESSABILITY | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1996-12-24 | — | — | US | disclosed |
| EP-0633896-A1 | ESTERIFIED STARCH COMPOSITION | National Starch and Chemical Investment Holding Corporation (US) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993020141-A1 | BIODEGRADABLE STARCH DERIVATIVE COMPOSITIONS | PARKE-DAVIS & COMPANY (US) | 1993-10-14 | — | — | WO | disclosed |
| WO-1993020110-A1 | ESTERIFIED STARCH COMPOSITION | PARKE-DAVIS & COMPANY (US) | 1993-10-14 | — | — | WO | disclosed |
| US-4361558-A | PREPARATION OF THESE ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-11-30 | — | — | US | disclosed |
| US-4201778-A | 6-Acyloxy-1,4,6-pregnatrienes, their use as anti-inflammatory agents, methods for their manufacture, and 6-oxo-1,4-pregnadiene intermediates | SCHERING CORPORATION (US) | 1980-05-06 | — | — | US | disclosed |
| EP-0001864-A1 | Novel 6-oxygenated-3,20-dioxo-pregnane derivatives, process for the preparation thereof, and pharmaceutical compositions containing them | Technobiotic Ltd. (CH) | 1979-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029918-A1 | Novel antibiotic compounds | DUOX1, MPO, OTUB1 | ESR1 451/4885FFAR3 3527/4885LCK 3521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.