SCHEMBL4328663

SCHEMBL4328663

[c]1ncccc1-c1cccc2c1[nH]c1ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.47
PARP14 Q460N5 9/20 0.45
KIF11 P52732 4/20 0.44
TDO2 P48775 3/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
MAPT P10636 1/20 0.43
GABRA1 P14867 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
NFKB1 P19838 1/20 0.43
MAOA P21397 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL277101 0.76 PARP14 (0.48) BCHEPARP14KIF11GABRPGABRD
SCHEMBL208113 0.76 KIF11 (0.63) BCHEPARP14KIF11GABRPGABRD
SCHEMBL29733506 0.76 KIF11 (0.63) BCHEPARP14KIF11GABRPGABRD
SCHEMBL980073 0.75 BCHE (0.55) BCHEPARP14KIF11TDO2KDM4E
SCHEMBL51674 0.74 KIF11 (0.61) BCHEPARP14KIF11GABRPGABRD
SCHEMBL191654 0.74 KIF11 (0.61) BCHEPARP14KIF11GABRPGABRD
SCHEMBL30521516 0.74 KIF11 (0.61) BCHEPARP14KIF11GABRPGABRD
SCHEMBL1115099 0.74 NISCH (0.41) BCHEKDM4EALDH1A1CYP3A4MAPT
Lithium SCHEMBL31282245 0.73 KIF11 (0.59) BCHEPARP14KIF11GABRPGABRD
SCHEMBL29986379 0.72 BCHE (0.56) BCHEPARP14KIF11TDO2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2018090-A1 ORGANIC ELECTROLUMINESCENT DEVICE Idemitsu Kosan Co., Ltd. (JP) 2009-01-21 EP disclosed