SCHEMBL4329104

SCHEMBL4329104

COC(CCNc1nc(NCCC(OC)C2CC(C)(C)NC(C)(C)C2)nc(N(CCCNc2nc(NCCC(OC)C3CC(C)(C)NC(C)(C)C3)nc(N(CCC(OC)C3CC(C)(C)N(c4nc(NCCC(OC)C5CC(C)(C)NC(C)(C)C5)nc(NCCC(OC)C5CC(C)(C)NC(C)(C)C5)n4)C(C)(C)C3)c3nc(NCCC(OC)C4CC(C)(C)NC(C)(C)C4)nc(NCCC(OC)C4CC(C)(C)NC(C)(C)C4)n3)n2)CCNCCCN)n1)C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8745440 0.89
SCHEMBL9398587 0.85 SMN1; SMN2 (0.32)
SCHEMBL4345117 0.84
SCHEMBL4329680 0.81
SCHEMBL8870597 0.79
SCHEMBL9861700 0.72 KCNH3 (0.33)
SCHEMBL10908393 0.72 KCNH3 (0.33)
SCHEMBL9398606 0.71 SMN1; SMN2 (0.36)
SCHEMBL9439977 0.70
SCHEMBL10816785 0.69 GBA1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090054565-A1 Flame-Retardant plastics molding composition CLARIANT INTERNATIONAL LTD. 2009-02-26 US disclosed
EP-2028227-A1 Flame-resistant plastic moulding material CLARIANT INTERNATIONAL LTD. (CH) 2009-02-25 EP disclosed
US-20080203593-A1 Polyvinyl Acetal-Containing Granulate, Method for the Production and the Utilization Thereof KURARAY EUROPE GMBH (DE) 2008-08-28 US disclosed
EP-1658323-B1 POLYVINYL ACETAL-CONTAINING GRANULATE, METHOD FOR THE PRODUCTION AND THE UTILIZATION THEREOF KURARAY EUROPE GMBH (DE) 2008-02-20 EP disclosed
US-6013706-A Process for the preparation of hyrolysis-stable trivalent phosphorus compounds and their use as stabilizers for thermoplastics CLARIANT GMBH (DE) 2000-01-11 US disclosed
EP-0668283-B1 Process for the preparation of polyalkyl-1-oxadiazaspirodecane compounds CLARIANT GMBH (DE) 1998-05-20 EP disclosed
US-5594142-A USING SOLVENT MIXTURE AND BASIC CATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1997-01-14 US disclosed
US-5550242-A REACTION CARRIED OUT IN INERT ORGANIC SOLVENT IN PRESENCE OF SOLID ALKALI METAL HYDROXIDE OR A MIXTURE OF HYDROXIDE AND WATER; AVOIDS USE OF PHASE TRANSFER CATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-27 US disclosed
EP-0668283-A1 Process for the preparation of polyalkyl-1-oxadiazaspirodecane compounds HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-23 EP disclosed
EP-0668282-A1 Process for the preparation of polyalkyl-1-oxadiazaspirodecane compounds HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-23 EP disclosed
US-5356967-A Raeacting formed Grignard reagent with a chloro-dibenzooxa-phosphorine derivative HOECHST AKTIENGESELLSCHAFT (DE) 1994-10-18 US disclosed
EP-0472564-B1 ARYLESTERS OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS, IN PARTICULAR POLYOLEFIN MOULDING MATERIALS HOECHST AG (DE) 1994-09-21 EP disclosed
US-5331034-A Deactivation of catalyst residues with ditrimethylolpropane HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-19 US disclosed
EP-0599284-A1 Cyclo-olefin polymer moulding composition with improved stability against chemical degradation HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-01 EP disclosed
US-5298541-A Molding materials HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-29 US disclosed
EP-0576833-A2 Process for preparing hydrolytically stable trivalent phosphorus compounds and their use as stabilisators for thermoplastic materials HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-05 EP disclosed
EP-0568999-A1 Polyvinylbutyrales having improved thermostability and light stability HOECHST AKTIENGESELLSCHAFT (DE) 1993-11-10 EP disclosed
EP-0489050-A1 ARYL ESTER AMIDE HALIDES OF PHOSPHONOUS ACID, ARYL ESTER AMIDES OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS HOECHST AKTIENGESELLSCHAFT (DE) 1992-06-10 EP disclosed
WO-1991002738-A1 ARYL ESTER AMIDE HALIDES OF PHOSPHONOUS ACID, ARYL ESTER AMIDES OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-07 WO disclosed
WO-1990014349-A2 ARYLESTERS OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS, IN PARTICULAR POLYOLEFIN MOULDING MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-29 WO disclosed