Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460205 | 0.95 | HRH3 (0.61) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL4462029 | 0.92 | SLC6A4 (0.50) | SLC6A4HRH3 | |
| SCHEMBL4462683 | 0.92 | HRH3 (0.55) | SLC6A4HRH3 | |
| SCHEMBL4329182 | 0.89 | SLC6A4 (0.47) | SLC6A4HRH3 | |
| SCHEMBL4466983 | 0.88 | HRH3 (0.46) | SLC6A4HRH3 | |
| SCHEMBL4338664 | 0.85 | SLC6A4 (0.48) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL4326089 | 0.85 | SLC6A4 (0.45) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL4475719 | 0.84 | FKBP1A (0.49) | NPC1KDM4EALDH1A1 | |
| SCHEMBL4321649 | 0.84 | SLC6A4 (0.47) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL4472671 | 0.83 | HRH3 (0.52) | SLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |