Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 14/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 13/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 13/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 13/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MLNR | O43193 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4322704 | 0.85 | OPRM1 (0.69) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL4327355 | 0.81 | OPRM1 (0.58) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL4325566 | 0.80 | OPRM1 (0.73) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL4331756 | 0.79 | OPRM1 (0.72) | OPRL1OPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL4327297 | 0.78 | OPRM1 (0.68) | OPRL1OPRM1OPRD1OPRK1SLC6A9 | |
| SCHEMBL13964192 | 0.77 | OPRL1 (0.74) | OPRL1OPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL4331585 | 0.77 | OPRM1 (0.63) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL4330933 | 0.77 | OPRM1 (0.59) | OPRL1OPRM1OPRD1OPRK1SLC6A9 | |
| SCHEMBL4319710 | 0.77 | OPRM1 (0.66) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL4331167 | 0.76 | OPRM1 (0.71) | OPRL1OPRM1OPRD1OPRK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069340-A1 | Pyrazolone Compounds As Metabotropic Glutamate Receptor Agonists For The Treatment Of Neurological And Psychiatric Disorders | ASTRAZENECA AB (SE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069340-A1 | Pyrazolone Compounds As Metabotropic Glutamate Receptor Agonists For The Treatment Of Neurological And Psychiatric Disorders | GRIN1, GRM1, GRIN3A | OPRL1 96/4885OPRM1 264/4885OPRD1 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.