Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.73 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5097463 | 0.85 | HRH3 (1.00) | HRH3 | |
| SCHEMBL18033539 | 0.83 | HRH3 (0.58) | HRH3 | |
| SCHEMBL4320078 | 0.81 | HRH3 (0.59) | HRH3 | |
| SCHEMBL24358934 | 0.80 | HRH3 (0.58) | HRH3 | |
| SCHEMBL5100700 | 0.80 | HRH3 (0.91) | HRH3 | |
| SCHEMBL8176556 | 0.78 | HRH3 (0.59) | HRH3 | |
| SCHEMBL14287752 | 0.78 | HRH3 (0.80) | HRH3 | |
| SCHEMBL10071518 | 0.77 | HRH3 (0.55) | HRH3 | |
| SCHEMBL6071411 | 0.76 | HRH3 (1.00) | HRH3 | |
| SCHEMBL18033541 | 0.76 | HRH3 (0.50) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |