SCHEMBL4330091

SCHEMBL4330091

CCCCCCCCC(C)(c1ccc(Oc2ccc(N)cc2)cc1)c1ccc(Oc2ccc(N)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.57
NPC1 O15118 3/20 0.57
RAB9A P51151 3/20 0.57
ALDH1A1 P00352 5/20 0.54
HPGD P15428 1/20 0.54
MAPK1 P28482 1/20 0.54
CNR2 P34972 4/20 0.47
CNR1 P21554 3/20 0.47
TDP1 Q9NUW8 3/20 0.44
TSHR P16473 3/20 0.44
CYP3A4 P08684 2/20 0.44
TEAD4 Q15561 1/20 0.42
POLB P06746 1/20 0.41
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
PDE4D Q08499 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
LTA4H P09960 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5179113 1.00 MAPT (0.57) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL6363490 1.00 MAPT (0.57) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL6361875 1.00 MAPT (0.57) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL3141298 1.00 MAPT (0.57) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL6363522 1.00 MAPT (0.57) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL5179603 1.00 MAPT (0.57) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL4339280 1.00 MAPT (0.57) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL6362740 1.00 MAPT (0.57) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL4328660 1.00 MAPT (0.57) MAPTNPC1RAB9AALDH1A1HPGD
SCHEMBL6362542 1.00 MAPT (0.57) MAPTNPC1RAB9AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0282254-B1 DIAMINO COMPOUNDS AND LIQUID CRYSTAL ALIGNING FILMS CHISSO CORPORATION (JP) 1993-06-16 EP claimed
US-4864008-A POLYIMIDE MONOMERS CHISSO CORPORATION (JP) 1989-09-05 US claimed
EP-0282254-A2 Diamino compounds and liquid crystal aligning films CHISSO CORPORATION (JP) 1988-09-14 EP claimed
US-20150185512-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND SUBSTRATE USED IN SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-07-02 US disclosed
US-20130021546-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND SUBSTRATE USED IN SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2013-01-24 US disclosed
US-7615260-B2 Active-matrix liquid crystal display HITACHI, LTD. (JP) 2009-11-10 US disclosed
EP-0933139-B1 THIN FILM COATER, COATING METHOD, AND METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORP (JP) 2007-06-13 EP disclosed
US-6949281-B1 Varnish composition and liquid-crystal display element CHISSO CORPORATION (JP) 2005-09-27 US disclosed
US-20050012884-A1 Active-matrix liquid crystal display IPS ALPHA SUPPORT CO., LTD. (JP) 2005-01-20 US disclosed
EP-0806698-B1 In-plane switching-mode active-matrix liquid crystal display HITACHI LTD (JP) 2005-01-12 EP disclosed
US-6756089-B2 MULTILAYER; POLYAMIDEIMIDE COPOLYMER HITACHI, LTD. (JP) 2004-06-29 US disclosed
US-6242060-B1 MULTILAYER HITACHI, LTD. (JP) 2001-06-05 US disclosed
EP-0933139-A1 THIN FILM COATER, COATING METHOD, AND METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1999-08-04 EP disclosed
EP-0806698-A1 Active-matrix liquid crystal display HITACHI, LTD. (JP) 1997-11-12 EP disclosed
US-5625475-A SUBJECTING ALIGNING FILM ON TRANSPARENT SUBSTRATE WITH TRANSPARENT ELECTRODE TO RUBBING TREATMENT AND THEN IRRADIATING WITH SOFT X-RAYS IN A GAS CHISSO CORPORATION (JP) 1997-04-29 US disclosed
US-5447759-A Liquid crystal alignment film and liquid crystal display element CHISSO CORPORATION (JP) 1995-09-05 US disclosed
EP-0282254-B1 DIAMINO COMPOUNDS AND LIQUID CRYSTAL ALIGNING FILMS CHISSO CORPORATION (JP) 1993-06-16 EP disclosed
US-5084557-A Polyimides based on a 2,2-bis/p-/p-aminophenoxy/phenylalkane; a high pretilt angle for supertwisting nematic mode display cells CHISSO CORPORATION (JP) 1992-01-28 US disclosed
US-4864008-A POLYIMIDE MONOMERS CHISSO CORPORATION (JP) 1989-09-05 US disclosed
EP-0282254-A2 Diamino compounds and liquid crystal aligning films CHISSO CORPORATION (JP) 1988-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130021546-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND SUBSTRATE USED IN SAME ZKSCAN2, L1CAM, SDC2 MAPT 114/4885NPC1 3351/4885RAB9A 2853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.