⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21657438 | 0.95 | ADH1B (0.48) | — | |
| SCHEMBL22419958 | 0.95 | ADH1B (0.48) | — | |
| SCHEMBL9574479 | 0.95 | ADH1B (0.48) | — | |
| SCHEMBL3032693 | 0.86 | ADH1B (0.56) | — | |
| SCHEMBL612872 | 0.86 | — | — | |
| SCHEMBL6007627 | 0.84 | ADH1B (0.58) | — | |
| SCHEMBL10940490 | 0.84 | ADH1B (0.48) | — | |
| SCHEMBL3465685 | 0.83 | — | — | |
| SCHEMBL8342441 | 0.82 | ADH1B (0.52) | — | |
| SCHEMBL24798454 | 0.81 | ADH1B (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008055-B1 | TETRAZOLONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2017-07-19 | — | — | EP | claimed |
| EP-3008055-A1 | NOVEL TETRAZOLONE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2016-04-20 | — | — | EP | claimed |
| US-20160083357-A1 | NOVEL TETRAZOLONE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2016-03-24 | — | — | US | claimed |
| WO-2014198592-A1 | NOVEL TETRAZOLONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2014-12-18 | — | — | WO | claimed |
| US-20080275022-A1 | Substituted Quinazolones as Anti-Cancer Agents | ASTRAZENECA AB (SE) | 2008-11-06 | — | — | US | claimed |
| EP-1761506-A1 | SUBSTITUTED QUINAZOLONES AS ANTI-CANCER AGENTS | AstraZeneca AB (SE) | 2007-03-14 | — | — | EP | claimed |
| WO-2005123696-A1 | SUBSTITUTED QUINAZOLONES AS ANTI-CANCER AGENTS | ASTRAZENECA AB (SE) | 2005-12-29 | — | — | WO | claimed |
| US-5206433-A | PREPARATION OF FORMIC ACID | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-27 | — | — | US | claimed |
| US-5059713-A | Selective catalytic cracking of carboxylic acid amides with magnesium sulfide and mixed oxides catalyst | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-10-22 | — | — | US | claimed |
| EP-0238357-B1 | 1,2,4-TRIAZINONE DERIVATIVES, THEIR PREPARATION AND USE | Sankyo Company Limited (JP) | 1991-05-29 | — | — | EP | claimed |
| CN-1010012-B | PREPARATION OF FORMIC ACID | BASF AG (DE) | 1990-10-17 | — | — | CN | claimed |
| EP-0161544-B1 | PROCESS FOR THE PREPARATION OF FORMIC ACID | BASF Aktiengesellschaft (DE) | 1988-03-02 | — | — | EP | claimed |
| CN-85104491-A | The preparation of formic acid | — | 1986-12-10 | — | — | CN | claimed |
| EP-0161544-A2 | Process for the preparation of formic acid | BASF Aktiengesellschaft (DE) | 1985-11-21 | — | — | EP | claimed |
| WO-2024071216-A1 | PYRAZOLE COMPOUND AND PEST CONTROL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | 三井化学クロップ＆ライフソリューション株式会社 | 2024-04-04 | — | — | WO | disclosed |
| WO-2023210759-A1 | ELECTRET AND ELECTRET FILTER | 東洋紡エムシー株式会社 | 2023-11-02 | — | — | WO | disclosed |
| WO-2023189803-A1 | RESIST UNDERLAYER FILM FORMING COMPOSITION | 日産化学株式会社 | 2023-10-05 | — | — | WO | disclosed |
| EP-0186817-A1 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-09 | — | — | EP | disclosed |
| EP-0171217-A2 | Fused-ring heterocyclic compounds a process for their production and their pharmaceutical use | SANKYO COMPANY LIMITED (JP) | 1986-02-12 | — | — | EP | disclosed |
| EP-0082109-A2 | Substituted 2-hydroxyphenylacetic acids and derivatives of them | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | disclosed |