Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4339765 | 0.85 | ALDH1A1 (0.36) | LMNASMN1; SMN2KDM4EALDH1A1TSHR | |
| SCHEMBL2993050 | 0.85 | NOTUM (0.31) | NOTUM | |
| SCHEMBL7517437 | 0.84 | CA1 (0.36) | ABL1NR4A2LMNAMAPTKDM4E | |
| SCHEMBL7517349 | 0.83 | KDM4E (0.37) | ABL1LMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL9126683 | 0.80 | ABL1 (0.38) | ABL1NR4A2LMNASMN1; SMN2MAPT | |
| SCHEMBL9127773 | 0.79 | GAA (0.38) | ABL1NR4A2LMNASMN1; SMN2MAPT | |
| SCHEMBL4346537 | 0.74 | NR1H4 (0.41) | LMNAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL19792699 | 0.73 | ABL1 (0.41) | ABL1NR4A2LMNASMN1; SMN2MAPT | |
| SCHEMBL5405325 | 0.72 | ALDH1A1 (0.33) | ABL1LMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL19756389 | 0.72 | NR4A2 (0.49) | NR4A2LMNAMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112274-B1 | CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ P (US) | 2009-12-09 | — | — | EP | disclosed |
| EP-2048140-A1 | Deuterated chemiluminescent 1,2-dioxetanes | Giri, Brij P. (US) | 2009-04-15 | — | — | EP | disclosed |
| US-7422908-B2 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P | 2008-09-09 | — | — | US | disclosed |
| US-7416898-B2 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P | 2008-08-26 | — | — | US | disclosed |
| EP-1453822-A4 | DEUTERIUM-BASED CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ P (US) | 2004-11-24 | — | — | EP | disclosed |
| EP-1453822-A2 | DEUTERIUM-BASED CHEMILUMINESCENT 1,2-DIOXETANES | Giri, Brij P. (US) | 2004-09-08 | — | — | EP | disclosed |
| US-20040077018-A1 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P (US) | 2004-04-22 | — | — | US | disclosed |
| US-20030213940-A1 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P (US) | 2003-11-20 | — | — | US | disclosed |
| WO-2003054506-A2 | DEUTERIUM-BASED CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ PAL (US) | 2003-07-03 | — | — | WO | disclosed |
| US-6461876-B1 | STABLE SPIROFUSED RINGS; DECOMPOSING TO GENERATE LIGHT AND CARBONYL GROUP; HIGH ENERGY; MEDICINE | TOBEN, HOWARD R. | 2002-10-08 | — | — | US | disclosed |
| EP-1112274-A4 | CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ P (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-1112274-A1 | CHEMILUMINESCENT 1,2-DIOXETANES | Giri, Brij P. (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000014092-A1 | CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ P (US) | 2000-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077018-A1 | Chemiluminescent 1,2-dioxetanes | CYP19A1, CYP1A1, CYP2F1 | ABL1 1349/4885NR4A2 1187/4885LMNA 2716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.