SCHEMBL4331007

SCHEMBL4331007

[CH2]C(OC(=O)C=C)OC(=O)C=C

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.41
ALDH1A1 P00352 6/20 0.39
TP53 P04637 3/20 0.39
HIF1A Q16665 3/20 0.39
CYP3A4 P08684 2/20 0.39
HSD17B10 Q99714 1/20 0.39
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HPGD P15428 1/20 0.34
FGFR4 P22455 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27313236 0.80
SCHEMBL27494684 0.79 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3902627 0.79 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1618752 0.78
SCHEMBL10758866 0.77
SCHEMBL2754225 0.77 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL30938817 0.77 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28840907 0.76
SCHEMBL28765427 0.76
SCHEMBL25921 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1489158-B1 Friction modifier composition SANYO CHEMICAL IND LTD (JP) 2012-06-20 EP disclosed
US-7579305-B2 Friction regulator for lubricating oil and lubricating oil composition SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2009-08-25 US disclosed
US-20070287644-A1 LUBRICATING OIL COMPOSITION SHELL OIL COMPANY 2007-12-13 US disclosed
EP-1860175-A2 Lubricating oil composition SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2007-11-28 EP disclosed
US-20060105924-A1 Friction regulator for lubricating oil and lubricating oil composition SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2006-05-18 US disclosed
EP-1489158-A1 FRICTION REGULATOR FOR LUBRICATING OIL AND LUBRICATING OIL COMPOSITION SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2004-12-22 EP disclosed
EP-0264827-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1993-01-07 EP disclosed
US-4833116-A MULTILAYER, COLOR IMAGES KANZAKI PAPER MFG. CO., LTD. (JP) 1989-05-23 US disclosed
EP-0264827-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1988-04-27 EP disclosed
US-4351881-A WEAR RESISTANCE, DYEABILITY MITSUBISHI RAYON CO., LTD. (JP) 1982-09-28 US disclosed
US-4291097-A PHOTOPOLYMERIZATION OF AN ACRYLIC ESTER MIXTURE WITH PHOSPHORIC ACID ESTER AND AN ETHANOLAMINE MITSUBISHI RAYON CO., LTD. (JP) 1981-09-22 US disclosed
US-4274933-A FORMING A CROSSLINKED HARDENED FILM ON A SUBSTRATE MITSUBISHI RAYON CO., LTD. (JP) 1981-06-23 US disclosed