SCHEMBL43312

SCHEMBL43312

CCc1cc(CC)c(N)c(C)c1N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.47
HTT P42858 2/20 0.47
MAPT P10636 2/20 0.47
POLB P06746 2/20 0.46
NOS3 P29474 2/20 0.41
NOS2 P35228 2/20 0.41
NOS1 P29475 1/20 0.41
TSHR P16473 2/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15256860 0.90 ALDH1A1 (0.44) ALDH1A1HTTMAPTPOLBNOS3
SCHEMBL1334753 0.89 HTT (0.41) ALDH1A1HTTMAPTPOLBNOS3
SCHEMBL31329205 0.87 ALDH1A1 (0.52) ALDH1A1HTTMAPTPOLBNOS3
SCHEMBL1333373 0.87 ALDH1A1 (0.52) ALDH1A1HTTMAPTPOLBNOS3
SCHEMBL9722554 0.85 ALDH1A1 (0.46) ALDH1A1HTTMAPTPOLBNOS3
SCHEMBL15397674 0.85 CYP3A4 (0.56) ALDH1A1HTTMAPTPOLBNOS3
SCHEMBL29568739 0.84 ALDH1A1 (0.44) ALDH1A1HTTMAPTPOLBNOS3
SCHEMBL20210748 0.84 ALDH1A1 (0.44) ALDH1A1HTTMAPTPOLBNOS3
Benzidine SCHEMBL29113244 0.83 ALDH1A1 (0.42) ALDH1A1HTTMAPTPOLBNOS3
SCHEMBL5141175 0.83 ALDH1A1 (0.45) ALDH1A1HTTMAPTPOLBNOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7826 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724510-A1 USE OF POLYURETHANE ELASTOMERS BASED ON OR USE OF KIT-OF-PARTS COMPRISING MDI-POLYADIPATE PREPOLYMERS AND POLYAMINE CHAIN-EXTENDERS IN PULP AND PAPER APPLICATIONS, PREFERABLY IN THE MANUFACTURE OF DIE CUTTING PADS, ANVIL COVERS, ROLLERS AND ZERO CRUSH WHEELS Covestro Deutschland AG (DE) 2026-04-15 EP claimed
US-20260091462-A1 PAD FOR CHEMICAL MECHANICAL POLISHING DUPONT ELECTRONIC MAT HOLDING INC (US) 2026-04-02 US claimed
US-20250353961-A1 METHOD FOR EXTENSION OF THE SHELF LIFE OF POSITIVE TYPE PHOTOSENSITIVE POLYIMIDE PRECURSORS IN SOLUTION AKRON POLYMER SYSTEMS INC (US) 2025-11-20 US claimed
US-20250250460-A1 COATING KIT AND METHOD FOR REPAIR AND/OR RECONSTITUTION OF RUBBER AND/OR METAL WORN AREAS BERTECH PANAMA S.A. (PA) 2025-08-07 US claimed
CN-115322330-B Thermoplastic and elastomeric polyurethanes derived from biobased 1, 5-pentamethylene diisocyanate 摩珈 (上海) 生物科技有限公司 2025-05-27 CN claimed
CN-119823535-A Sealing resin composition, cured product, electronic component device, and method for manufacturing electronic component device 株式会社力森诺科 2025-04-15 CN claimed
CN-119772780-A Polishing layer, polishing pad, and method for manufacturing semiconductor device 湖北鼎汇微电子材料有限公司 2025-04-08 CN claimed
CN-119734199-A Polishing layer, polishing pad and polishing method 湖北鼎汇微电子材料有限公司 2025-04-01 CN claimed
WO-2025048359-A1 SOLVENT-SOLUBLE POLYIMIDE WITH SIMPLIFIED PREPARATION PROCESS AND PREPARATION METHOD THEREFOR 피아이첨단소재 주식회사 2025-03-06 WO claimed
CN-118755440-B Insulating adhesive, positive plate and secondary battery 深圳好电科技有限公司 2025-02-11 CN claimed
US-4456541-A Antioxidant diamine ETHYL CORPORATION (US) 1984-06-26 US claimed
EP-0044481-B1 PROCESS FOR THE PRODUCTION OF ELASTOMERIC MOULDED PRODUCTS Mobay Chemical Corporation (US) 1984-06-13 EP claimed
EP-0081729-A1 Use of liquid cold-setting polyurethane forming components for corrosion-retardant and wear-protecting coatings of metallic and plastics surfaces and moulded articles, and of stone and concrete BAYER AG (DE) 1983-06-22 EP claimed
EP-0022497-B1 PROCESS FOR THE PREPARATION OF ELASTIC, OPTIONALLY CELLULAR POLYURETHANE UREAS BAYER AG (DE) 1983-05-11 EP claimed
US-4379105-A Process for the production of elastic shaped articles MOBAY CHEMICAL CORPORATION (US) 1983-04-05 US claimed
EP-0075130-A2 Improved reaction injection molding process THE DOW CHEMICAL COMPANY (US) 1983-03-30 EP claimed
US-4374210-A MOLDING MATERIALS; LONG GELATION TIME; STOICHIOMETRY; INJECTION MOLDING THE UPJOHN COMPANY (US) 1983-02-15 US claimed
EP-0044481-A1 Process for the production of elastomeric moulded products Mobay Chemical Corporation (US) 1982-01-27 EP claimed
US-4296212-A MOLDING MATERIALS THE UPJOHN COMPANY (US) 1981-10-20 US claimed
US-4218543-A REACTION INJECTION MOLDING BAYER AKTIENGESELLSCHAFT (DE) 1980-08-19 US claimed