Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 10/20 | 0.39 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.37 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.37 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.37 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.36 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578312 | 0.98 | PDE2A (0.40) | PDE2AGUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| Trifluoroacetic Acid SCHEMBL4328532 | 0.87 | GUCY1B2 (0.39) | PDE2AGUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| Trifluoroacetic Acid SCHEMBL4323359 | 0.86 | SCN9A (0.38) | PDE2ASCN9ACD38CNR2 | |
| SCHEMBL13578313 | 0.84 | SCN9A (0.39) | PDE2ASCN9ACD38CNR2 | |
| Trifluoroacetic Acid SCHEMBL4331013 | 0.84 | CNR2 (0.40) | PDE2AGUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| Trifluoroacetic Acid SCHEMBL4326012 | 0.84 | CNR2 (0.45) | PDE2AGUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL13578303 | 0.83 | GUCY1B2 (0.41) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CD38 | |
| Trifluoroacetic Acid SCHEMBL4332745 | 0.82 | CD38 (0.36) | PDE2AGUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| Trifluoroacetic Acid SCHEMBL4329692 | 0.82 | CD38 (0.42) | PDE2ACD38CNR2 | |
| Trifluoroacetic Acid SCHEMBL4325295 | 0.81 | CNR2 (0.35) | PDE2AGUCY1B2GUCY1A2GUCY1A1GUCY1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK & CO., INC. | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | CNR2, CNR1, TRPV1 | PDE2A 964/4885GUCY1B2 1139/4885GUCY1A2 1180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.