Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MAST3 | O60307 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.34 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.34 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.34 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | PKLR | P30613 | 4/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578314 | 0.95 | CD38 (0.39) | CD38DYRK1AAKT1CNR2MAST3 | |
| Trifluoroacetic Acid SCHEMBL4328532 | 0.85 | GUCY1B2 (0.39) | CD38CNR2CNR1MAST3MAPK8 | |
| Trifluoroacetic Acid SCHEMBL4323359 | 0.84 | SCN9A (0.38) | CD38CNR2PDE2A | |
| SCHEMBL13578313 | 0.82 | SCN9A (0.39) | CD38CNR2PDE2A | |
| Trifluoroacetic Acid SCHEMBL4329692 | 0.82 | CD38 (0.42) | CD38DYRK1ACNR2MAST3MAPK8 | |
| Trifluoroacetic Acid SCHEMBL4331256 | 0.82 | PDE2A (0.39) | CD38CNR2CNR1GUCY1B2GUCY1A2 | |
| SCHEMBL13578303 | 0.81 | GUCY1B2 (0.41) | CD38DYRK1ACNR2CNR1MAST3 | |
| Trifluoroacetic Acid SCHEMBL4329931 | 0.81 | DYRK1A (0.49) | CD38DYRK1AL3MBTL1PDE2A | |
| Trifluoroacetic Acid SCHEMBL4331013 | 0.81 | CNR2 (0.40) | CD38DYRK1ACNR2CNR1GUCY1B2 | |
| Trifluoroacetic Acid SCHEMBL4326012 | 0.80 | CNR2 (0.45) | CD38CNR2CNR1MAST3MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK & CO., INC. | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | CNR2, CNR1, TRPV1 | CD38 785/4885DYRK1A 1478/4885AKT1 2591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.