SCHEMBL4331530

SCHEMBL4331530

C=C1[C@H](O[Si](C)(C)C(C)(C)C)CC(=CC(=O)O)C[C@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2688348 0.86
SCHEMBL14523029 0.80
SCHEMBL3187924 0.79 PPM1D (0.34)
SCHEMBL10041393 0.79
SCHEMBL2687928 0.78 STAT3 (0.32)
SCHEMBL9010536 0.77
SCHEMBL13796072 0.77
SCHEMBL6429594 0.76
SCHEMBL6429595 0.76
SCHEMBL628761 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7598408-B2 Intermediates for synthesis of vitamin D derivatives KNC LABORATORIES CO., LTD. (JP) 2009-10-06 US disclosed
US-20060106242-A1 Novel intermediates for synthesis of vitamin d derivatives KNC LABORATORIES CO., LTD. (JP) 2006-05-18 US disclosed
EP-1598360-A1 NOVEL INTERMEDIATES FOR SYNTHESIS OF VITAMIN D DERIVATIVES KNC Laboratories Co., Ltd (JP) 2005-11-23 EP disclosed