Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 11/20 | 0.44 |
| ▸ | NPY1R | P25929 | 6/20 | 0.44 |
| ▸ | NPY2R | P49146 | 4/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | NMT2 | O60551 | 2/20 | 0.36 |
| ▸ | NMT1 | P30419 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2407969 | 0.92 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| SCHEMBL30423428 | 0.89 | FOLH1 (0.54) | NPY4RNPY1RNPY2RNPY5RFOLH1 | |
| SCHEMBL31171160 | 0.89 | FOLH1 (0.54) | NPY4RNPY1RNPY2RNPY5RFOLH1 | |
| SCHEMBL30045741 | 0.89 | FOLH1 (0.54) | NPY4RNPY1RNPY2RNPY5RFOLH1 | |
| SCHEMBL31452998 | 0.89 | FOLH1 (0.54) | NPY4RNPY1RNPY2RNPY5RFOLH1 | |
| SCHEMBL30414248 | 0.89 | FOLH1 (0.54) | NPY4RNPY1RNPY2RNPY5RFOLH1 | |
| SCHEMBL29902836 | 0.89 | FOLH1 (0.54) | NPY4RNPY1RNPY2RNPY5RFOLH1 | |
| SCHEMBL4595320 | 0.89 | FOLH1 (0.54) | NPY4RNPY1RNPY2RNPY5RFOLH1 | |
| SCHEMBL31420018 | 0.89 | FOLH1 (0.54) | NPY4RNPY1RNPY2RNPY5RFOLH1 | |
| SCHEMBL27613292 | 0.89 | FOLH1 (0.54) | NPY4RNPY1RNPY2RNPY5RFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143584-A1 | TREATMENT OF PULMONARY EDEMA | VEGENICS LIMITED (AU) | 2009-12-03 | — | — | WO | disclosed |