Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | ENPP1 | P22413 | 5/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.50 |
| ▸ | ENPP3 | O14638 | 4/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GPR17 | Q13304 | 4/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4326069 | 0.85 | KMT2A (0.48) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL4648365 | 0.85 | MAOB (0.56) | KMT2AMEN1MAPTALDH1A1MAOB | |
| SCHEMBL22187248 | 0.82 | MAPT (0.64) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL29671363 | 0.82 | MAPT (0.64) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL10212054 | 0.79 | MAPT (0.58) | KMT2AMEN1MAPTRECQLNR4A1 | |
| SCHEMBL29673614 | 0.78 | MAPT (0.68) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL22187449 | 0.78 | MAPT (0.68) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL8393963 | 0.78 | HSD11B1 (0.62) | KMT2AMEN1MAPTALDH1A1RECQL | |
| SCHEMBL9000081 | 0.78 | STS (0.53) | KMT2AMEN1ALDH1A1MAOBSMN1; SMN2 | |
| SCHEMBL29673269 | 0.78 | STS (0.53) | KMT2AMEN1ALDH1A1MAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |