Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR4 | P46093 | 11/20 | 0.78 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.78 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4332351 | 1.00 | GPR4 (0.78) | GPR4KCNH2HRH3 | |
| SCHEMBL4365527 | 0.94 | GPR4 (0.81) | GPR4KCNH2HRH3 | |
| SCHEMBL4365521 | 0.94 | GPR4 (0.81) | GPR4KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL4323632 | 0.94 | GPR4 (0.79) | GPR4KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL4323628 | 0.94 | GPR4 (0.79) | GPR4KCNH2HRH3 | |
| SCHEMBL4371858 | 0.94 | GPR4 (0.85) | GPR4KCNH2HRH3 | |
| SCHEMBL4371852 | 0.94 | GPR4 (0.85) | GPR4KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL4336803 | 0.93 | GPR4 (0.84) | GPR4KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL4336797 | 0.93 | GPR4 (0.84) | GPR4KCNH2HRH3 | |
| SCHEMBL4335071 | 0.88 | GPR4 (0.87) | GPR4KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144201-A1 | IMIDAZOPYRIDINE DERIVATIVES AS GPR4 RECEPTOR MODULATORS | NOVARTIS AG (CH) | 2009-12-03 | — | — | WO | disclosed |