Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25317454 | 0.76 | SLC18A3 (0.33) | DDB1CRBNALDH1A1KDM4EMAPT | |
| SCHEMBL29437813 | 0.73 | DDB1 (0.39) | DDB1CRBNALDH1A1KDM4EMAPT | |
| SCHEMBL13889929 | 0.70 | KDM4E (0.44) | DDB1CRBNALDH1A1KDM4EMAPT | |
| SCHEMBL659325 | 0.70 | KDM4E (0.48) | DDB1CRBNALDH1A1KDM4EMAPT | |
| SCHEMBL29448519 | 0.70 | — | — | |
| SCHEMBL900225 | 0.70 | — | — | |
| SCHEMBL10317513 | 0.70 | SLC6A4 (0.43) | KDM4E | |
| SCHEMBL13863010 | 0.70 | DDB1 (0.36) | DDB1CRBNALDH1A1KDM4EMAPT | |
| SCHEMBL8427103 | 0.67 | — | — | |
| SCHEMBL13674926 | 0.67 | OPRM1 (0.38) | DDB1CRBNALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071500-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-06-11 | — | — | WO | disclosed |
| WO-2006089038-A3 | INSECTICIDAL TETRAHYDROINDENOPYRIDINE DERIVATIVES | FMC CORP (US) | 2007-01-11 | — | — | WO | disclosed |
| WO-2006089038-A2 | INSECTICIDAL TETRAHYDROINDENOPYRIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2006-08-24 | — | — | WO | disclosed |