Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.40 |
| ▸ | PPARA | Q07869 | 12/20 | 0.40 |
| ▸ | PPARD | Q03181 | 8/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4334795 | 0.93 | PPARG (0.40) | PPARGPPARAPPARDAAK1FFAR1 | |
| SCHEMBL6652618 | 0.87 | PPARG (0.44) | PPARGPPARAPPARD | |
| SCHEMBL13819374 | 0.84 | MRGPRX4 (0.47) | PPARGPPARAPPARDAAK1MRGPRX4 | |
| SCHEMBL4336975 | 0.83 | MRGPRX4 (0.43) | PPARGPPARAPPARDFFAR1MRGPRX4 | |
| SCHEMBL4327930 | 0.83 | MRGPRX4 (0.43) | PPARGPPARAPPARDFFAR1MRGPRX4 | |
| SCHEMBL4327927 | 0.83 | MRGPRX4 (0.43) | PPARGPPARAPPARDFFAR1MRGPRX4 | |
| SCHEMBL4332539 | 0.82 | PPARA (0.50) | PPARGPPARAPPARDFFAR1MRGPRX4 | |
| SCHEMBL4332536 | 0.82 | PPARA (0.50) | PPARGPPARAPPARDFFAR1MRGPRX4 | |
| SCHEMBL4339171 | 0.82 | PPARA (0.50) | PPARGPPARAPPARDFFAR1MRGPRX4 | |
| SCHEMBL4328248 | 0.81 | SCN4A (0.46) | PPARGPPARAPPARDMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |