Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.40 |
| ▸ | PPARA | Q07869 | 8/20 | 0.40 |
| ▸ | PPARD | Q03181 | 6/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4333095 | 0.93 | PPARG (0.40) | PPARGPPARAPPARDAAK1FFAR1 | |
| SCHEMBL4335146 | 0.89 | PPARA (0.54) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL4333447 | 0.89 | PPARA (0.54) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL4333444 | 0.89 | PPARA (0.54) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL6652728 | 0.87 | PPARG (0.44) | PPARGPPARAPPARD | |
| SCHEMBL4334110 | 0.87 | PPARG (0.49) | PPARGPPARAPPARDKDM4E | |
| SCHEMBL4334214 | 0.87 | PPARG (0.49) | PPARGPPARAPPARDKDM4E | |
| SCHEMBL4334218 | 0.87 | PPARG (0.49) | PPARGPPARAPPARDKDM4E | |
| SCHEMBL4340686 | 0.86 | AAK1 (0.42) | PPARGPPARAPPARDAAK1KDM4E | |
| SCHEMBL4328595 | 0.84 | PPARG (0.46) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |