Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578152 | 0.94 | KDM4E (0.55) | KDM4EMAP2K3ALDH1A1HTTROCK2 | |
| Trifluoroacetic Acid SCHEMBL4327655 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1HTTSMN1; SMN2TSHR | |
| Trifluoroacetic Acid SCHEMBL4339626 | 0.83 | MAP2K3 (0.53) | KDM4EMAP2K3ALDH1A1ROCK1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4321534 | 0.80 | MAP2K3 (0.51) | MAP2K3CNR1 | |
| Trifluoroacetic Acid SCHEMBL4325507 | 0.79 | MAP2K3 (0.50) | MAP2K3ROCK2CNR1CNR2 | |
| Trifluoroacetic Acid SCHEMBL4325899 | 0.78 | MAP2K3 (0.54) | KDM4EMAP2K3ALDH1A1KMT2ACNR2 | |
| SCHEMBL13578215 | 0.78 | KDM4E (0.59) | KDM4EALDH1A1HTTTSHRCNR1 | |
| Trifluoroacetic Acid SCHEMBL4327668 | 0.76 | MAP2K3 (0.48) | KDM4EMAP2K3HTTKMT2ACNR1 | |
| Trifluoroacetic Acid SCHEMBL4326035 | 0.76 | MAP2K3 (0.53) | KDM4EMAP2K3ALDH1A1KMT2ACNR1 | |
| SCHEMBL13578146 | 0.76 | MAP2K3 (0.60) | KDM4EMAP2K3ALDH1A1ROCK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK & CO., INC. | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | CNR2, CNR1, TRPV1 | KDM4E 2430/4885MAP2K3 1970/4885ALDH1A1 2838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.