Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K3 | P46734 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 8/20 | 0.42 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | WNT1 | P04628 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578146 | 0.93 | MAP2K3 (0.60) | MAP2K3RORCRAD51ROCK1HTR4 | |
| Trifluoroacetic Acid SCHEMBL4336494 | 0.90 | RORC (0.44) | MAP2K3RORCHTR4PPARGCNR1 | |
| Trifluoroacetic Acid SCHEMBL4321534 | 0.87 | MAP2K3 (0.51) | MAP2K3RORCHTR4PPARGCNR1 | |
| Trifluoroacetic Acid SCHEMBL4325507 | 0.86 | MAP2K3 (0.50) | MAP2K3RORCHTR4CNR1WNT1 | |
| Trifluoroacetic Acid SCHEMBL4318631 | 0.85 | ATM (0.45) | RORCHTR4PPARG | |
| Trifluoroacetic Acid SCHEMBL4327668 | 0.84 | MAP2K3 (0.48) | MAP2K3RORCHTR4PPARGCNR1 | |
| SCHEMBL13578189 | 0.84 | MAP2K3 (0.45) | MAP2K3RORCRAD51HTR4PPARG | |
| Trifluoroacetic Acid SCHEMBL4333533 | 0.83 | KDM4E (0.49) | MAP2K3ROCK1CNR1KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4325479 | 0.82 | MAP2K3 (0.46) | MAP2K3RORCHTR4CNR1HIF1A | |
| Trifluoroacetic Acid SCHEMBL4325899 | 0.82 | MAP2K3 (0.54) | MAP2K3RORCRAD51HTR4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK & CO., INC. | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | CNR2, CNR1, TRPV1 | MAP2K3 1970/4885RORC 135/4885RAD51 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.