Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.49 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HAT1 | O14929 | 2/20 | 0.35 |
| ▸ | EP300 | Q09472 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4329955 | 1.00 | CNR2 (0.49) | CNR2HTR4CYP3A4HAT1EP300 | |
| SCHEMBL13578225 | 0.93 | CNR2 (0.52) | CNR2HTR4ALDH1A1KDM4EKMT2A | |
| SCHEMBL13578226 | 0.93 | CNR2 (0.52) | CNR2HTR4ALDH1A1KDM4EKMT2A | |
| Trifluoroacetic Acid SCHEMBL4328508 | 0.84 | PDE2A (0.38) | CNR2HTR4CYP3A4RORCPPARG | |
| Trifluoroacetic Acid SCHEMBL4324553 | 0.83 | ATM (0.46) | CNR2RORCPPARG | |
| Trifluoroacetic Acid SCHEMBL4329948 | 0.83 | ATM (0.46) | CNR2RORCPPARG | |
| Trifluoroacetic Acid SCHEMBL4341277 | 0.83 | CNR2 (0.46) | CNR2HTR4CYP3A4RORCPPARG | |
| Trifluoroacetic Acid SCHEMBL4341766 | 0.83 | CNR2 (0.55) | CNR2HTR4CYP3A4RORCPPARG | |
| Trifluoroacetic Acid SCHEMBL4327394 | 0.83 | MAP2K3 (0.54) | CNR2HTR4CYP3A4RORCPPARG | |
| Trifluoroacetic Acid SCHEMBL4324541 | 0.83 | CNR2 (0.46) | CNR2HTR4RORCPPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK & CO., INC. | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | CNR2, CNR1, TRPV1 | CNR2 1/4885HTR4 254/4885CYP3A4 761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.