Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 7/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578000 | 0.93 | MAPK1 (0.40) | RORCMAPK3MAPK1THRBROCK2 | |
| Trifluoroacetic Acid SCHEMBL4329929 | 0.86 | RORC (0.47) | RORCPPARGMAPK3MAPK1 | |
| Trifluoroacetic Acid SCHEMBL4326992 | 0.84 | RORC (0.44) | PDE2ARORCPPARG | |
| Trifluoroacetic Acid SCHEMBL4329955 | 0.84 | CNR2 (0.49) | RORCPPARGCYP3A4HTR4CNR2 | |
| Trifluoroacetic Acid SCHEMBL4333546 | 0.84 | CNR2 (0.49) | RORCPPARGCYP3A4HTR4CNR2 | |
| Trifluoroacetic Acid SCHEMBL4318940 | 0.80 | CTSA (0.38) | PDE2APPARGMAPK3MAPK1HDAC3 | |
| Trifluoroacetic Acid SCHEMBL4341766 | 0.80 | CNR2 (0.55) | RORCPPARGCYP3A4HTR4CNR2 | |
| SCHEMBL13578164 | 0.79 | RORC (0.48) | RORCPPARGMAPK3MAPK1 | |
| Trifluoroacetic Acid SCHEMBL4338398 | 0.78 | PHGDH (0.44) | PDE2AMAPK1ROCK2ROCK1 | |
| Trifluoroacetic Acid SCHEMBL4329744 | 0.77 | CNR2 (0.66) | PDE2ACYP2C9CYP3A4HTR4CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK & CO., INC. | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | CNR2, CNR1, TRPV1 | PDE2A 964/4885RORC 135/4885PPARG 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.