Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1467437 | 0.94 | TSHR (0.44) | TSHRALDH1A1CYP3A4HCAR2CHRM2 | |
| SCHEMBL2727797 | 0.85 | TSHR (0.50) | TSHRALDH1A1CYP3A4HCAR2THRB | |
| SCHEMBL10349931 | 0.81 | TSHR (0.43) | TSHRALDH1A1CYP3A4HCAR2HPGD | |
| SCHEMBL9159446 | 0.79 | HCAR2 (0.46) | TSHRALDH1A1CYP3A4HCAR2HPGD | |
| SCHEMBL9159437 | 0.79 | HCAR2 (0.46) | TSHRALDH1A1CYP3A4HCAR2HPGD | |
| SCHEMBL10349929 | 0.79 | TSHR (0.45) | TSHRALDH1A1CYP3A4HCAR2HPGD | |
| Trimethylammonium SCHEMBL8522437 | 0.79 | TSHR (0.45) | TSHRALDH1A1CYP3A4HCAR2HPGD | |
| SCHEMBL5890320 | 0.79 | HCAR2 (0.46) | TSHRALDH1A1CYP3A4HCAR2HPGD | |
| Benzene SCHEMBL28102584 | 0.77 | TSHR (0.41) | TSHRALDH1A1CYP3A4HCAR2THRB | |
| SCHEMBL434162 | 0.77 | TSHR (0.49) | TSHRALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010918-A2 | OPTICAL DEVICES | MEDICONTUR ORVOSTECHNIKAI KFT. (HU) | 2012-01-26 | — | — | WO | disclosed |