SCHEMBL434162

SCHEMBL434162

C=CC(=O)OC(C)OC(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.49
TP53 P04637 1/20 0.49
PDCD1 Q15116 1/20 0.47
CD274 Q9NZQ7 1/20 0.47
LMNA P02545 5/20 0.45
NPC1 O15118 5/20 0.45
RAB9A P51151 4/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
HTT P42858 2/20 0.45
ALDH1A1 P00352 1/20 0.45
AKT1 P31749 1/20 0.44
F2 P00734 1/20 0.42
POLB P06746 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
SCN1A P35498 1/20 0.40
SCN2A Q99250 1/20 0.40
SCN3A Q9NY46 1/20 0.40
MAPT P10636 3/20 0.40
CA12 O43570 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4645541 0.89 MAPT (0.43) TSHRTP53PDCD1CD274LMNA
SCHEMBL8982606 0.89 RAB9A (0.42) TSHRTP53PDCD1CD274NPC1
SCHEMBL8982618 0.86 SMN1; SMN2 (0.42) TSHRTP53NPC1RAB9ASMN1; SMN2
SCHEMBL1249525 0.86 LMNA (0.47) TSHRTP53PDCD1CD274LMNA
SCHEMBL6660758 0.86 TSHR (0.63) TSHRTP53PDCD1CD274LMNA
SCHEMBL6872719 0.85 AKR1C3 (0.44) TSHRLMNAALDH1A1AKT1CYP1A2
SCHEMBL301790 0.85 TSHR (0.43) TSHRLMNANPC1SMN1; SMN2ALDH1A1
SCHEMBL10728252 0.84 CA1 (0.41) PDCD1CD274LMNANPC1RAB9A
SCHEMBL301791 0.83 ALDH1A1 (0.48) TSHRLMNANPC1ALDH1A1CYP1A2
Acetic Acid SCHEMBL1273751 0.82 TSHR (0.59) TSHRTP53PDCD1CD274LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489623-A APPLYING POLYMER TO SURFACE, EXPOSING TO INCIDENT PHOTONICRADIATION TO RENDER PORTIONS LESS SOLUBLE OR DISPERSIBLE THE DOW CHEMICAL COMPANY (US) 1996-02-06 US claimed
EP-0454379-B1 Thermal transfer image-receiving sheet OJI PAPER CO (JP) 1994-12-07 EP claimed
US-5234885-A THERMAL TRANSFER IMAGE-RECEIVING SHEET OJI PAPER CO., LTD. (JP) 1993-08-10 US claimed
EP-0454379-A1 Thermal transfer image-receiving sheet OJI PAPER CO. LTD. (JP) 1991-10-30 EP claimed
EP-3505522-B1 SURFACE TREATMENT METHOD, SURFACE TREATMENT AGENT, AND NOVEL COMPOUND MORI KUNIO (JP) 2020-10-14 EP disclosed
US-10385076-B2 Surface treatment agent and novel compound Mori, Kunio (JP) 2019-08-20 US disclosed
EP-3505522-A1 SURFACE TREATMENT METHOD, SURFACE TREATMENT AGENT, AND NOVEL COMPOUND Mori, Kunio (JP) 2019-07-03 EP disclosed
EP-2859962-B1 SURFACE TREATMENT METHOD, SURFACE TREATMENT AGENT, AND NOVEL COMPOUND MORI KUNIO (JP) 2019-01-23 EP disclosed
US-20170334933-A1 SURFACE TREATMENT AGENT AND NOVEL COMPOUND Mori, Kunio (JP) 2017-11-23 US disclosed
US-9790242-B2 Surface treatment method, surface treatment agent, and novel compound Mori, Kunio (JP) 2017-10-17 US disclosed
US-9593423-B2 Process for forming metal film, and product equipped with metal film Mori, Kunio (JP) 2017-03-14 US disclosed
US-9540403-B2 Bonding method, bondability improving agent, surface modification method, surface modifying agent, and novel compound Mori, Kunio (JP) 2017-01-10 US disclosed
US-4771085-A TALC AND-OR MICA DISPERSED IN ACRYLATED RUBBER MODIFIED EPOXY RESIN OLIGOMER, ACRYLATED POLYDIENE OLIGOMER AND ALKYL ACRYLATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-09-13 US disclosed
US-4752598-A USING AN ACRYLATED POLYESTERURETHANE DYE RECEIVING SHEET MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1988-06-21 US disclosed
EP-0264037-A2 UV-curable dielectric compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-04-20 EP disclosed
EP-0129234-B1 ELECTROPHOTOGRAPHIC ELEMENTS HAVING BARRIER LAYERS OF CROSSLINKED POLYMERS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-11-04 EP disclosed
EP-0209359-A2 Dye receiving sheet for heat-transfer recording MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1987-01-21 EP disclosed
EP-0129234-A1 Electrophotographic elements having barrier layers of crosslinked polymers EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-12-27 EP disclosed
US-4485161-A Electrophotographic elements having barrier layers of crosslinked polymers of aliphatic or aromatic monomers containing α,β-ethylenically unsaturated carbonyl-containing substituents EASTMAN KODAK COMPANY (US) 1984-11-27 US disclosed
US-4322490-A Photopolymerizable compositions featuring improved monomers EASTMAN KODAK COMPANY (US) 1982-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170334933-A1 SURFACE TREATMENT AGENT AND NOVEL COMPOUND EPCAM, MET, ITGAM TSHR 619/4885TP53 241/4885PDCD1 2620/4885
US-10385076-B2 Surface treatment agent and novel compound EPCAM, MET, ITGAM TSHR 619/4885TP53 241/4885PDCD1 2620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.