SCHEMBL4333677

SCHEMBL4333677

CC1([N+](=O)[O-])[CH]N=CC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8725615 0.67
SCHEMBL5547954 0.61
SCHEMBL27623082 0.59 KCNA4 (0.30)
SCHEMBL3713102 0.59
SCHEMBL28005305 0.57
SCHEMBL18687689 0.53
SCHEMBL20030014 0.52
SCHEMBL10592329 0.49
SCHEMBL27570798 0.49
SCHEMBL651428 0.46 MEN1 (0.75)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090162293-A1 METHODS AND COMPOSITIONS FOR ULTRASOUND IMAGING OF APOPTOSIS POINT BIOMEDICAL CORPORATION (US) 2009-06-25 US disclosed
EP-1673108-A4 METHODS AND COMPOSITIONS FOR ULTRASOUND IMAGING OF APOPTOSIS POINT BIOMEDICAL CORP (US) 2009-06-03 EP disclosed
US-7413727-B2 Contrast agents GE HEALTHCARE AS (NO) 2008-08-19 US disclosed
EP-1442751-B1 Diagnostic imaging technique GE HEALTHCARE AS (NO) 2007-06-20 EP disclosed
US-7182934-B2 Ultrasonic contrast agents; aqueous suspension GE HEALTHCARE AS (NO) 2007-02-27 US disclosed
EP-1673108-A2 METHODS AND COMPOSITIONS FOR ULTRASOUND IMAGING OF APOPTOSIS Point Biomedical Corporation (US) 2006-06-28 EP disclosed
EP-1007101-B1 IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS GE HEALTHCARE AS (NO) 2006-05-17 EP disclosed
EP-0973552-B1 IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS AMERSHAM HEALTH AS (NO) 2006-03-01 EP disclosed
EP-0971747-B1 CONTRAST AGENTS AMERSHAM HEALTH AS (NO) 2005-12-28 EP disclosed
US-20050201930-A1 Contrast agents GE HEALTHCARE AS (NO) 2005-09-15 US disclosed
EP-0977600-A2 CONTRAST AGENTS NYCOMED IMAGING A/S (NO) 2000-02-09 EP disclosed
EP-0971747-A2 CONTRAST AGENTS NYCOMED IMAGING AS (NO) 2000-01-19 EP disclosed
EP-0963209-A2 IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS Marsden, John Christopher (GB) 1999-12-15 EP disclosed
EP-0946202-A2 CONTRAST AGENTS NYCOMED IMAGING AS (NO) 1999-10-06 EP disclosed
WO-1998047541-A1 CONTRAST AGENTS NYCOMED IMAGING AS (NO) 1998-10-29 WO disclosed
WO-1998018497-A2 CONTRAST AGENTS NYCOMED IMAGING AS (NO) 1998-05-07 WO disclosed
WO-1998018496-A2 CONTRAST AGENTS NYCOMED IMAGING AS (NO) 1998-05-07 WO disclosed
WO-1998018500-A2 IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS MARSDEN, JOHN, CHRISTOPHER (GB) 1998-05-07 WO disclosed
WO-1998018498-A2 IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS MARSDEN, JOHN, CHRISTOPHER (GB) 1998-05-07 WO disclosed
WO-1998018495-A2 IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS MARSDEN, JOHN, CHRISTOPHER (GB) 1998-05-07 WO disclosed