Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.46 |
| ▸ | RELA | Q04206 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14302348 | 0.96 | LMNA (0.43) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL14500157 | 0.96 | NPC1 (0.49) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL3192599 | 0.96 | NPC1 (0.49) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL13768006 | 0.95 | NPC1 (0.47) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL13785271 | 0.95 | NPC1 (0.42) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL497301 | 0.94 | MAPT (0.47) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL14301931 | 0.94 | NPC1 (0.41) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL14308573 | 0.94 | LMNA (0.44) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL30457050 | 0.93 | MAPT (0.40) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL18589724 | 0.93 | NPC1 (0.46) | NPC1LMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169293-B1 | LIQUID CRYSTAL COMPOUNDS | ROLIC AG (CH) | 2009-07-22 | — | — | EP | disclosed |
| EP-1169293-B1 | LIQUID CRYSTAL COMPOUNDS | ROLIC AG (CH) | 2009-07-22 | — | — | EP | disclosed |
| US-6733690-B1 | ACRYLIC ESTER POLYMERS | ROLIC AG (CH) | 2004-05-11 | — | — | US | disclosed |
| EP-1169293-A1 | LIQUID CRYSTAL COMPOUNDS | Rolic AG (CH) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000055110-A1 | LIQUID CRYSTAL COMPOUNDS | ROLIC AG (CH) | 2000-09-21 | — | — | WO | disclosed |