SCHEMBL43337

SCHEMBL43337

Cc1ccccc1C[NH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2095297 0.79 ESR1 (0.44)
SCHEMBL5236129 0.79 TAAR1 (0.60)
SCHEMBL1696970 0.78 HSPA5 (0.38)
Hydrochloric Acid SCHEMBL650455 0.78 TAAR1 (0.52)
SCHEMBL29477327 0.77 TAAR1 (0.56)
SCHEMBL2090458 0.77 TAAR1 (0.56)
SCHEMBL143962 0.77 TAAR1 (0.71)
Hydrochloric Acid SCHEMBL7921306 0.76 TAAR1 (0.62)
SCHEMBL5609796 0.75 TAAR1 (0.56)
SCHEMBL773959 0.75 ALDH1A1 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 480 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112094218-B Synthesis method of pyrrole derivative 湖北科技学院 2024-01-26 CN claimed
CN-108780273-B Photosensitive colored resin composition, color filter and manufacturing method thereof, and display device DNP精细化工股份有限公司 2022-06-28 CN claimed
CN-112457363-B Potato trisaccharide oleanolic acid saponin derivative and preparation method and application thereof 华南农业大学 2021-12-24 CN claimed
CN-112457363-A Potato trisaccharide oleanolic acid saponin derivative and preparation method and application thereof 华南农业大学 2021-03-09 CN claimed
US-20190053492-A1 SUBSTITUTED PYRIDINE COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2019-02-21 US claimed
US-9884839-B2 Inhibitors of 17Beta-hydroxysteroid dehydrogenases type 1 and type 2 ELEXOPHARM GMBH (DE) 2018-02-06 US claimed
EP-2888252-B1 BENZOFURAZAN ANTI-AMYLOID COMPOUNDS AND METHODS TREVENTIS CORP (US) 2017-06-07 EP claimed
EP-3089969-A2 INHIBITORS OF 17BETA-HYDROXYSTEROID DEHYDROGENASES TYPE 1 AND TYPE 2 Elexopharm GmbH (DE) 2016-11-09 EP claimed
US-20160318895-A1 Inhibitors of 17Beta-Hydroxysteroid Dehydrogenases Type 1 and Type 2 ELEXOPHARM GMBH (DE) 2016-11-03 US claimed
US-20160264535-A1 BENZOFURAZAN ANTI-AMYLOID COMPOUNDS AND METHODS TREVENTIS CORPORATION (US) 2016-09-15 US claimed
EP-0330910-A1 Propane derivatives KOWA COMPANY, LTD. (JP) 1989-09-06 EP claimed
EP-0169470-A2 Mixture, manufacturing process and application as a drug BAYER AG (DE) 1986-01-29 EP claimed
US-4550162-A Process for the manufacture of enol derivatives CIBA-GEIGY CORPORATION (US) 1985-10-29 US claimed
US-4518596-A Antithrombotic use of 2-(perhydro-1,4-diazino)-pyrimido (5,4,D)-pyrimidines DR. KARL THOMAE GMBH (DE) 1985-05-21 US claimed
EP-0063826-B1 2-AMINO-BENZOIC-ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES OR INTERMEDIATES Dr. Karl Thomae GmbH (DE) 1984-12-05 EP claimed
US-4319027-A Process for the manufacture of ceohem enol derivatives CIBA-GEIGY CORPORATION (US) 1982-03-09 US claimed
US-4293462-A Process for the manufacture of enol derivatives, and intermediates CIBA-GEIGY CORPORATION (US) 1981-10-06 US claimed
US-4268510-A DEMETHANIZATION, METABOLISM, RUMEN IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-05-19 US claimed
US-4207320-A FUNGICIDES WARNER-LAMBERT COMPANY (US) 1980-06-10 US claimed
US-4110533-A PROCESS FOR THE MANUFACTURE OF ENOL DERIVATIVES CIBA-GEIGY CORPORATION (US) 1978-08-29 US claimed