Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.78 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.78 |
| ▸ | CCR5 | P51681 | 4/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13613480 | 1.00 | CCR2 (0.78) | CCR2KCNH2CCR5 | |
| Trifluoroacetic Acid SCHEMBL4138388 | 0.97 | CCR2 (0.74) | CCR2KCNH2CCR5 | |
| SCHEMBL4338200 | 0.94 | CCR2 (0.77) | CCR2KCNH2CCR5 | |
| SCHEMBL13613478 | 0.94 | CCR2 (0.77) | CCR2KCNH2CCR5 | |
| SCHEMBL4331863 | 0.94 | CCR2 (0.79) | CCR2KCNH2CCR5 | |
| SCHEMBL13613458 | 0.93 | CCR2 (0.77) | CCR2KCNH2CCR5 | |
| SCHEMBL4335714 | 0.93 | CCR2 (0.77) | CCR2KCNH2CCR5 | |
| SCHEMBL4274362 | 0.93 | CCR2 (0.77) | CCR2KCNH2CCR5 | |
| SCHEMBL13335050 | 0.92 | CCR2 (0.66) | CCR2KCNH2CCR5 | |
| SCHEMBL3324618 | 0.92 | CCR2 (0.66) | CCR2KCNH2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618970-B2 | 3-aminocyclopentanecarboxamides as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2009-11-17 | — | — | US | claimed |