SCHEMBL433398

SCHEMBL433398

CCC/C=C(/NC(C)(C)C)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.37
GRIK2 Q13002 1/20 0.37
EP300 Q09472 1/20 0.34
KDM4C Q9H3R0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1847277 0.83 GRIK1 (0.33) GRIK1GRIK2KDM4C
SCHEMBL28092432 0.81 CYP3A4 (0.32)
SCHEMBL5693379 0.77 GRIK1 (0.40) GRIK1GRIK2EP300
SCHEMBL10791524 0.75 EP300 (0.41) EP300
SCHEMBL5693362 0.75 GRIK1 (0.39) GRIK1GRIK2EP300
SCHEMBL10011981 0.73 CA12 (0.37)
SCHEMBL2192227 0.72 GRIK1 (0.41) GRIK1GRIK2
SCHEMBL2495438 0.69 GRIK1 (0.46) GRIK1GRIK2
SCHEMBL7558903 0.68 EP300 (0.42) GRIK1GRIK2EP300
SCHEMBL7558899 0.68 EP300 (0.42) GRIK1GRIK2EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582684-B2 Macroporous ion exchange resins 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-09-01 US claimed
US-20250367610-A1 Block Copolymers Grafted to Porous Polymeric Substrate SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-12-04 US disclosed
EP-2588219-B1 FILTER PLATE ARTICLE HAVING A WATER-ABSORBENT FILTER ASSEMBLY NEOGEN FOOD SAFETY US HOLDCO CORP (US) 2024-05-29 EP disclosed
EP-2376689-B1 FUNCTIONALIZED NONWOVEN ARTICLE 3M INNOVATIVE PROPERTIES CO (US) 2023-09-13 EP disclosed
US-11279731-B2 Ligand functional substrates 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-03-22 US disclosed
EP-3326711-B1 GRAFT COPOLYMER FUNCTIONALIZED ARTICLE 3M INNOVATIVE PROPERTIES CO (US) 2021-07-07 EP disclosed
US-10988827-B2 Coalescing elements in copper production 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-04-27 US disclosed
EP-3255085-B1 LIGAND GRAFT FUNCTIONALIZED SUBSTRATES 3M INNOVATIVE PROPERTIES CO (US) 2020-06-10 EP disclosed
EP-2303437-B1 METHOD OF FORMING AN ASYMMETRIC MEMBRANE 3M INNOVATIVE PROPERTIES CO (US) 2020-06-10 EP disclosed
EP-2303438-B1 METHOD OF FORMING A REWETTABLE ASYMMETRIC MEMBRANE 3M INNOVATIVE PROPERTIES CO (US) 2020-06-03 EP disclosed
WO-2007078878-A1 FUNCTIONALIZED SUBSTRATES 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-07-12 WO disclosed
WO-2007078880-A1 METHOD OF MAKING FUNCTIONALIZED SUBSTRATES 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-07-12 WO disclosed
US-20070154703-A1 FUNCTIONALIZED SUBSTRATES 3M INNOVATIVE PROPERTIES COMPANY 2007-07-05 US disclosed
WO-2007075442-A2 METHOD OF MAKING MACROPOROUS ANION EXCHANGE RESINS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-07-05 WO disclosed
US-20070154651-A1 METHOD OF MAKING FUNCTIONALIZED SUBSTRATES 3M INNOVATIVE PROPERTIES COMPANY 2007-07-05 US disclosed
US-20070142590-A1 Method of making macroporous anion exchange resins 3M INNOVATIVE PROPERTIES COMPANY 2007-06-21 US disclosed
US-7098253-B2 particles of hydrophilic, crosslinked copolymers of N,N'-alkylenebis(meth)acrylamide and a sulfonated N,N'-alkylene bisacrylic amide; chromatographic columns, composite materials, filters; large furface area, ease of manufacture, low material cost, variety of fiber texture, densities 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-08-29 US disclosed
US-20050261384-A1 MACROPOROUS ION EXCHANGE RESINS 3M INNOVATIVE PROPERTIES COMPANY 2005-11-24 US disclosed
US-20050261385-A1 Macroporous ion exchange resins 3M INNOVATIVE PROPERTIES COMPANY 2005-11-24 US disclosed
US-5576403-A EFFICIENCY NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1996-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11279731-B2 Ligand functional substrates PCNA, POLM, POLL GRIK1 1438/4885GRIK2 1753/4885EP300 3423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.