SCHEMBL1847277

SCHEMBL1847277

CC/C=C(/NC(C)(C)C)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.33
GRIK2 Q13002 1/20 0.33
EGFR P00533 1/20 0.32
NPC1 O15118 2/20 0.31
MAPT P10636 2/20 0.31
LMNA P02545 1/20 0.31
CASP3 P42574 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
KDM4C Q9H3R0 1/20 0.31
EPHX1 P07099 1/20 0.30
ALPL P05186 1/20 0.30
ALPI P09923 1/20 0.30
ALPG P10696 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL433398 0.83 GRIK1 (0.37) GRIK1GRIK2KDM4C
SCHEMBL1346930 0.81 ALDH1A1 (0.33)
SCHEMBL28125437 0.79 TET2 (0.32)
SCHEMBL2349984 0.75
SCHEMBL22739266 0.75
SCHEMBL2049219 0.73 GRIK1 (0.35) GRIK1GRIK2
SCHEMBL4939289 0.71
SCHEMBL629548 0.71 GRIK1 (0.34) GRIK1GRIK2
SCHEMBL15525384 0.71 MEN1 (0.37)
SCHEMBL2190700 0.70 GRIK1 (0.37) GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1784435-B1 METHODS FOR PRODUCING CROSSLINKABLE OLIGOMERS NUPLEX RESINS BV (NL) 2009-11-11 EP claimed
EP-1694725-B1 AMPHOLYTIC ANIONIC COPOLYMERS BASF SE (DE) 2009-09-02 EP claimed
EP-1093787-B1 Composition for treating dandruff based on a pyridinethione salt, an insoluble conditioning agent and an acrylic terpolymer OREAL (FR) 2007-03-14 EP claimed
EP-1694725-A1 AMPHOLYTIC ANIONIC COPOLYMERS BASF AKTIENGESELLSCHAFT (DE) 2006-08-30 EP claimed
WO-2005058988-A1 AMPHOLYTIC ANIONIC COPOLYMERS BASF AKTIENGESELLSCHAFT (DE) 2005-06-30 WO claimed
EP-0832159-B1 AUTOMOTIVE COATINGS FROM NON-AQUEOUS DISPERSIONS SHERWIN WILLIAMS CO (US) 2004-11-17 EP claimed
EP-1088546-B1 Composition for treating dandruff in hair and scalp based on an antidandruff agent and an acrylic terpolymer OREAL (FR) 2004-07-14 EP claimed
EP-1092420-B1 A washing composition for keratinous materials based on a surfactant, a cationic vinyllactam polymer and an acrylic terpolymer OREAL (FR) 2004-05-19 EP claimed
EP-1092419-B1 A washing composition for keratinous materials based on a surfactant, a polyorganosiloxane and an acrylic terpolymer OREAL (FR) 2004-02-25 EP claimed
EP-1090632-B1 A washing composition for keratinous materials based on a surfactant, a polyorganosiloxane, a cationic polymer and an acrylic terpolymer OREAL (FR) 2004-02-04 EP claimed
EP-1090622-B1 A washing composition for keratinous materials based on a surfactant, a functionalised silicone and an acrylic terpolymer OREAL (FR) 2003-01-22 EP claimed
EP-1088542-B1 Hair washing composition based on one detergent surfactant, one cationic galactomannan gum and one acrylic terpolymer OREAL (FR) 2002-07-10 EP claimed
EP-0824914-B1 Thickened personal care composition NAT STARCH CHEM INVEST (US) 2002-05-02 EP claimed
EP-0859796-B1 AQUEOUS COMPOSITIONS THICKENED WITH ACRYLATE-BASED POLYMERIC RHEOLOGY MODIFIERS NAT STARCH CHEM CORP (US) 2000-11-02 EP claimed
EP-2463349-B1 Fluorinated acrylic polymer compositions as fluid loss additives in drilling fluids 3M INNOVATIVE PROPERTIES CO (US) 2014-06-18 EP disclosed
EP-1915122-B1 COPOLYMERS FOR COSMETIC APPLICATIONS BASF SE (DE) 2013-12-04 EP disclosed
EP-2463349-A1 Fluorinated acrylic polymer compositions as fluid loss additives in drilling fluids 3M Innovative Properties Co. (US) 2012-06-13 EP disclosed
EP-0263306-A1 Reticulated polymer having silyl groups, its preparation and use in coating compositions BASF Lacke + Farben AG (DE) 1988-04-13 EP disclosed
EP-0261385-A2 Vehicle combination curable by curing agents, for use in aqueous dilutable coatings, cathodically depositable electrophoretic coating compositions, and their use Herberts Gesellschaft mit beschränkter Haftung (DE) 1988-03-30 EP disclosed
EP-0259647-A2 Externally cross-linkable binder combination, aqueous coating compositions containing it and its use Herberts Gesellschaft mit beschränkter Haftung (DE) 1988-03-16 EP disclosed