Glycine

Glycine

SCHEMBL433424

Cl.Cl.Cl.Cl.NCC(=O)O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycine SCHEMBL3505988 1.00
Glycine SCHEMBL1555637 1.00 GLRA1 (0.91)
Glycine SCHEMBL28861283 1.00 GLRA1 (0.91)
Glycine SCHEMBL6357710 1.00 GLRA1 (0.91)
Glycine SCHEMBL11056979 1.00 GLRA1 (0.91)
Glycine SCHEMBL37746 1.00
Glycine SCHEMBL5053459 1.00
Glycine SCHEMBL1650224 1.00 GLRA1 (0.91)
Glycine SCHEMBL3941221 0.96
Glycine SCHEMBL2163120 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250235531-A1 MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS MODERNATX, INC. (US) 2025-07-24 US disclosed
EP-4423107-A1 LIPID AMINES ModernaTX, Inc. (US) 2024-09-04 EP disclosed
WO-2023076598-A1 LIPID AMINES MODERNATX, INC. (US) 2023-05-04 WO disclosed
US-20230010214-A1 DEODORIZING COMPOSITION AQDOT LIMITED (GB) 2023-01-12 US disclosed
US-10988434-B2 Fragrance mixture SYMRISE AG (DE) 2021-04-27 US disclosed
EP-3432855-A1 ANTIPERSPIRANT STICK IN THE FORM OF A O/W EMULSION Beiersdorf AG (DE) 2019-01-30 EP disclosed
US-8828367-B2 Water-free antiperspirant non-aerosols in which active substances are more readily released HENKEL AG & CO. KGAA (DE) 2014-09-09 US disclosed
US-20120308486-A1 Fragrance and/or flavoring compositions containing dioxolanes SYMRISE AG (DE) 2012-12-06 US disclosed
EP-2480193-A1 WATER-FREE ANTIPERSPIRANT NON-AEROSOLS IN WHICH ACTIVE SUBSTANCES ARE MORE READILY RELEASED Henkel AG & Co. KGaA (DE) 2012-08-01 EP disclosed
US-20120177589-A1 WATER-FREE ANTIPERSPIRANT NON-AEROSOLS IN WHICH ACTIVE SUBSTANCES ARE MORE READILY RELEASED HENKEL AG & CO. KGAA (DE) 2012-07-12 US disclosed
US-20120107261-A1 COSMETIC COMPOSITIONS HAVING SUSPENSIONS OF SILVER SALTS HENKEL AG & CO. KGAA (DE) 2012-05-03 US disclosed
WO-2012010683-A2 DOUBLE SALT-CONTAINING ANTIPERSPIRANT STICKS HENKEL AG & CO. KGAA (DE) 2012-01-26 WO disclosed
US-20090220444-A1 Antiperspirant and Deodorant Compositions with Improved Protective Action HENKEL AG & CO. KGAA (DE) 2009-09-03 US disclosed
US-6835373-B2 A particulate antiperspirant active having a metal to chloride molar ratio of &lt;= to about 1.3, a volatile solvent, a low surface tension nonvolatile solvent and a suspending agent THE PROCTER & GAMBLE COMPANY 2004-12-28 US disclosed
US-6350460-B1 COMPOSITION COMPRISING STEARYL ALCOHOL, VOLATILE SILICONE, COSMETICALLY ACTIVE INGREDIENT, DIPROPYLENE GLYCOL, COSOLVENT WITH SOLUBILITY PARAMETER IN RANGE OF 19-20, AND HIGH MELTING POINT WAX COLGATE-PALMOLIVE COMPANY 2002-02-26 US disclosed
EP-0512770-B1 Clear gelled cosmetic compositions and process for production BRISTOL MYERS SQUIBB CO (US) 1996-10-02 EP disclosed
US-5376363-A Clear gelled antiperspirant stick composition BRISTOL-MYERS SQUIBB COMPANY (US) 1994-12-27 US disclosed
EP-0512770-A1 Clear gelled cosmetic compositions and process for production Bristol-Myers Squibb Company (US) 1992-11-11 EP disclosed