Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FASN | P49327 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 6/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946563 | 0.93 | PTGDR2 (0.42) | PTGDR2KDM4EMEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL5614018 | 0.92 | PTGDR2 (0.41) | PTGDR2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL5728643 | 0.81 | PTGDR2 (0.51) | PTGDR2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL27652147 | 0.81 | PTGDR2 (0.55) | PTGDR2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29490978 | 0.81 | KDM4E (0.50) | KDM4EMEN1MAPTKMT2AFASN | |
| SCHEMBL12488847 | 0.81 | PTGDR2 (0.48) | PTGDR2KDM4EMAPTNPC1RAB9A | |
| SCHEMBL18304696 | 0.80 | PTGDR2 (0.57) | PTGDR2NPC1RAB9ACAMKK2 | |
| SCHEMBL27436953 | 0.79 | PTGDR2 (0.44) | PTGDR2MAPTKMT2ANPC1RAB9A | |
| SCHEMBL30359453 | 0.78 | NPC1 (0.39) | PTGDR2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL27496581 | 0.78 | KDM4E (0.50) | KDM4EMEN1MAPTKMT2AFASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032142-A2 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-03-11 | — | — | EP | claimed |
| WO-2007147109-A2 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-12-21 | — | — | WO | claimed |