Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | CAMKK2 | Q96RR4 | 8/20 | 0.39 |
| ▸ | CAMKK1 | Q8N5S9 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17682016 | 0.93 | DRD2 (0.44) | PTGDR2NPC1RAB9ADRD2DRD4 | |
| SCHEMBL27652147 | 0.86 | PTGDR2 (0.55) | PTGDR2NPC1RAB9ADRD2DRD4 | |
| SCHEMBL18304696 | 0.85 | PTGDR2 (0.57) | PTGDR2NPC1RAB9ACAMKK2CAMKK1 | |
| SCHEMBL27832665 | 0.82 | PTGDR2 (0.51) | PTGDR2NPC1RAB9ADRD2DRD4 | |
| SCHEMBL4334283 | 0.81 | PTGDR2 (0.47) | PTGDR2NPC1RAB9ADRD2DRD4 | |
| SCHEMBL9220646 | 0.81 | PTGDR2 (0.50) | PTGDR2NPC1RAB9AKMT2AGAA | |
| SCHEMBL27832639 | 0.81 | PTGDR2 (0.53) | PTGDR2NPC1RAB9ADRD2DRD4 | |
| SCHEMBL27436953 | 0.80 | PTGDR2 (0.44) | PTGDR2NPC1RAB9ADRD2DRD4 | |
| SCHEMBL23981527 | 0.80 | CAMKK2 (0.41) | PTGDR2NPC1RAB9ACAMKK2CAMKK1 | |
| SCHEMBL7534043 | 0.80 | CHRNA1 (0.42) | PTGDR2CAMKK2CAMKK1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720836-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005082859-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2005-09-09 | — | — | WO | disclosed |