Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1542949 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KDM4EAPPDRD4DRD2 | |
| SCHEMBL16481262 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4EAPPDRD4DRD2 | |
| SCHEMBL16014765 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4EAPPDRD4DRD2 | |
| SCHEMBL16481270 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4EAPPDRD4DRD2 | |
| SCHEMBL5685402 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4EAPPDRD4DRD2 | |
| SCHEMBL941289 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4EAPPDRD4DRD2 | |
| SCHEMBL19496150 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EAPPDRD4DRD2 | |
| SCHEMBL614620 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KDM4EAPPDRD4DRD2 | |
| SCHEMBL14241918 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KDM4EAPPDRD4DRD2 | |
| SCHEMBL14227139 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KDM4EAPPDRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054493-A1 | THIAZOLE DERIVATIVES AS PPAR DELTA LIGANDS AND THEIR MANUFACTURING PROCESS | Kang, Heonjoong Kang (KR) | 2009-02-26 | — | — | US | disclosed |
| EP-1856072-A1 | THIAZOLE DERIVATIVES AS PPAR DELTA LIGANDS AND THEIR MANUFACTURING PROCESS | Kang, Heonjoong (KR) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006091047-A1 | THIAZOLE DERIVATIVES AS PPAR DELTA LIGANDS AND THEIR MANUFACTURING PROCESS | KANG HEONJOONG (KR) | 2006-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054493-A1 | THIAZOLE DERIVATIVES AS PPAR DELTA LIGANDS AND THEIR MANUFACTURING PROCESS | PPARD, PPARG, PPARA | ALDH1A1 789/4885KDM4E 3515/4885APP 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.