SCHEMBL433459

SCHEMBL433459

CCC(C#N)C(C)(C)O[SiH3]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6747549 0.82
SCHEMBL25946902 0.72
SCHEMBL25572380 0.69
SCHEMBL159852 0.69
SCHEMBL26104505 0.68
SCHEMBL119152 0.65
SCHEMBL28602135 0.65
SCHEMBL4142859 0.65
SCHEMBL4799989 0.65
SCHEMBL11287239 0.65 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3021948-B1 OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS OREAL (FR) 2019-08-21 EP disclosed
EP-2462197-B1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF ORÉAL L (FR) 2016-09-21 EP disclosed
WO-2016116488-A1 OIL/OIL EMULSION COMPRISING SOLID MICROPARTICLES, AT LEAST ONE HYDROCARBON-BASED RESIN, AT LEAST A FIRST OILY PHASE AND AT LEAST A SECOND OILY PHASE L'OREAL (FR) 2016-07-28 WO disclosed
WO-2016116475-A1 O/O EMULSION CONTAINING MICROPARTICLES WITH A BREAK IN THE CURVATURED PART, COMPOSITIONS COMPRISING SAME AND USE OF MICROPARTICLES FOR STABILIZING THE O/O EMULSIONS L'OREAL (FR) 2016-07-28 WO disclosed
WO-2016116492-A1 OIL/OIL EMULSION COMPRISING SOLID MICROPARTICLES, AT LEAST A FIRST OILY PHASE, AT LEAST A SECOND OILY PHASE AND AT LEAST A THIRD OILY PHASE THAT ARE MUTUALLY IMMISCIBLE L'OREAL (FR) 2016-07-28 WO disclosed
US-20160158118-A1 OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS L'OREAL (FR) 2016-06-09 US disclosed
EP-3021948-A1 OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS L'OREAL (FR) 2016-05-25 EP disclosed
EP-2462199-B1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF ORÉAL L (FR) 2015-05-20 EP disclosed
WO-2015008263-A1 OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS L'OREAL (FR) 2015-01-22 WO disclosed
US-20140335136-A1 COMPOSITIONS FOR MINIMIZING SKIN IMPERFECTIONS L'OREAL (FR) 2014-11-13 US disclosed
WO-2010109545-A1 POWDER COMPOSITION CONTAINING FUSIFORM PARTICLES FOR COSMETIC USE L'OREAL (FR) 2010-09-30 WO disclosed
WO-2010109546-A1 LIQUID COMPOSITION CONTAINING FUSIFORM PARTICLES FOR COSMETIC USE L'OREAL (FR) 2010-09-30 WO disclosed
US-20080145436-A1 Aqueous phase dispersed in an oily phase, a silicone emulsifier, a hydrophilic acrylic polymers and 2-acrylamido-2-methylpropanesulfonic acid polymers, and a silicon-based filler L'OREAL (FR) 2008-06-19 US disclosed
US-20080108535-A1 COMPOSITION CONTAINING HOLLOW HEMISPHERICAL PARTICLES L'OREAL (FR) 2008-05-08 US disclosed
US-20080044365-A1 Concave or annular particles of silicone materials for increasing the sun protection factor of aqueous photoprotective compositions comprising same L'OREAL (FR) 2008-02-21 US disclosed
US-20070154500-A1 COMPOSITION CONTAINING CONCAVE PARTICLES AND A DISPERSANT, PROCESSES AND USES L'OREAL (FR) 2007-07-05 US disclosed
US-20060293431-A1 Cosmetic composition comprising silicone particles L'OREAL S.A. (FR) 2006-12-28 US disclosed
US-20050220741-A1 Cosmetic composition comprising concave particles L'OREAL S.A. (FR) 2005-10-06 US disclosed
US-20050220740-A1 Cosmetic composition comprising concave particles L'OREAL S.A. (FR) 2005-10-06 US disclosed
WO-2002055986-A2 SAMPLE PRECONCENTRATION TUBES WITH SOL-GEL SURFACE COATINGS AND/OR SOL-GEL MONOLITHIC BEDS UNIV SOUTH FLORIDA (US) 2002-07-18 WO disclosed