Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.61 |
| ▸ | PPARD | Q03181 | 12/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13810392 | 0.94 | PPARA (0.56) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL4345261 | 0.90 | PPARA (0.55) | PPARAPPARDPPARG | |
| SCHEMBL4337850 | 0.90 | PPARA (0.59) | PPARAPPARDPPARGLDHAPSEN1 | |
| SCHEMBL4328750 | 0.89 | PPARA (0.56) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL4334358 | 0.87 | LDHA (0.52) | PPARALDHA | |
| SCHEMBL4340268 | 0.87 | LDHA (0.52) | PPARAPPARDPPARGLDHA | |
| SCHEMBL4340426 | 0.87 | LDHA (0.54) | PPARAPPARDPPARGLDHA | |
| SCHEMBL4338073 | 0.86 | LDHA (0.51) | PPARAPPARDPPARGLDHA | |
| SCHEMBL13810423 | 0.85 | PPARA (0.49) | PPARAPPARDPPARG | |
| SCHEMBL13810405 | 0.84 | PPARA (0.55) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |