Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.59 |
| ▸ | GLS | O94925 | 3/20 | 0.43 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026860 | 0.92 | HRH3 (0.65) | HRH3GLS | |
| SCHEMBL1025897 | 0.78 | HRH3 (0.59) | HRH3 | |
| Acetic Acid SCHEMBL1027146 | 0.76 | HRH3 (0.56) | HRH3GLS | |
| SCHEMBL14843948 | 0.74 | HRH3 (1.00) | HRH3 | |
| SCHEMBL21724875 | 0.72 | HRH3 (0.49) | HRH3GLSSMPD3 | |
| SCHEMBL4335029 | 0.71 | GLS (0.47) | HRH3GLS | |
| SCHEMBL17392419 | 0.70 | NOTUM (0.55) | — | |
| SCHEMBL17392415 | 0.70 | NOTUM (0.55) | — | |
| SCHEMBL2079085 | 0.69 | HRH3 (0.54) | HRH3 | |
| SCHEMBL24757887 | 0.69 | GLS (0.42) | HRH3GLSSMPD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009132202-A2 | MACROCYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS | INCYTE CORPORATION (US) | 2009-10-29 | — | — | WO | disclosed |