Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.54 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.54 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.54 |
| ▸ | CD69 | Q07108 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30679825 | 1.00 | ALDH1A1 (0.56) | ALDH1A1THRBP2RY14MAPK1P2RY2 | |
| SCHEMBL20281034 | 0.92 | ALDH1A1 (0.61) | ALDH1A1THRBP2RY14MAPK1P2RY2 | |
| Pyrophosphoric Acid SCHEMBL26646343 | 0.91 | ALDH1A1 (0.57) | ALDH1A1THRBP2RY14MAPK1P2RY2 | |
| SCHEMBL15334201 | 0.90 | ALDH1A1 (0.61) | ALDH1A1THRBP2RY14MAPK1P2RY2 | |
| SCHEMBL22410446 | 0.90 | ALDH1A1 (0.61) | ALDH1A1THRBP2RY14MAPK1P2RY2 | |
| SCHEMBL5679031 | 0.90 | ALDH1A1 (0.61) | ALDH1A1THRBP2RY14MAPK1P2RY2 | |
| SCHEMBL317138 | 0.90 | ALDH1A1 (0.61) | ALDH1A1THRBP2RY14MAPK1P2RY2 | |
| SCHEMBL20552181 | 0.90 | ALDH1A1 (0.61) | ALDH1A1THRBP2RY14MAPK1P2RY2 | |
| SCHEMBL7152633 | 0.90 | ALDH1A1 (0.61) | ALDH1A1THRBP2RY14MAPK1P2RY2 | |
| SCHEMBL18710872 | 0.90 | ALDH1A1 (0.61) | ALDH1A1THRBP2RY14MAPK1P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2596123-A2 | CRYSTAL STRUCTURE OF HUMAN ALPHA-N-ACETYLGLUCOSAMINIDASE | Shire Human Genetic Therapies, Inc. (US) | 2013-05-29 | — | — | EP | claimed |
| WO-2012012742-A2 | CRYSTAL STRUCTURE OF HUMAN ALPHA-N-ACETYLGLUCOSAMINIDASE | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2012-01-26 | — | — | WO | claimed |