Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR4 | P46093 | 9/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.77 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4335194 | 1.00 | GPR4 (0.77) | GPR4KCNH2HRH3 | |
| SCHEMBL4331227 | 0.97 | GPR4 (0.81) | GPR4KCNH2HRH3 | |
| SCHEMBL4331230 | 0.97 | GPR4 (0.81) | GPR4KCNH2HRH3 | |
| SCHEMBL4369574 | 0.96 | GPR4 (0.83) | GPR4KCNH2HRH3 | |
| SCHEMBL4369578 | 0.96 | GPR4 (0.83) | GPR4KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL4378795 | 0.95 | GPR4 (0.81) | GPR4KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL4378790 | 0.95 | GPR4 (0.81) | GPR4KCNH2HRH3 | |
| SCHEMBL4331414 | 0.91 | GPR4 (0.80) | GPR4KCNH2HRH3 | |
| SCHEMBL4331410 | 0.91 | GPR4 (0.80) | GPR4KCNH2HRH3 | |
| SCHEMBL4375125 | 0.89 | GPR4 (0.77) | GPR4KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144201-A1 | IMIDAZOPYRIDINE DERIVATIVES AS GPR4 RECEPTOR MODULATORS | NOVARTIS AG (CH) | 2009-12-03 | — | — | WO | disclosed |